{"title":"Serological evidence of Q fever in Tibetan sheep in Qinghai Province, China","authors":"Xiaomin Wu , Chao Chen , Te Ba , Lin Liang","doi":"10.1016/j.onehlt.2025.101233","DOIUrl":null,"url":null,"abstract":"<div><div>Q fever, caused by the obligate intracellular bacterium <em>Coxiella burnetii</em> (<em>C. burnetii</em>), is a global zoonotic disease. No data is available about <em>C. burnetii</em> infection in Tibetan sheep in Qinghai, China. In this study, 1043 Tibetan sheep serum samples (421 females and 622 males) were collected from 8 regions in Qinghai Province and examined for antibodies against <em>C. burnetii</em> using a commercial ELISA Kit. The overall seroprevalence of <em>C. burnetii</em> infection was 5.9 % (62/1043, 95 % CI 4.5–7.4). Interestingly, <em>C. burnetii</em> infection rates in Tibetan sheep showed no statistically significant correlations with age, geographical region, and gender (<em>P</em> > 0.05). The results of the present survey support the widespread presence of <em>C. burnetii</em> in Tibetan sheep in Qinghai, also providing baseline data for improving livestock management, preventing and controlling Q fever in large ruminants in the region. Further molecular epidemiological investigations are warranted to understand the epidemiology of <em>C. burnetii</em> transmission in Qinghai, China.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101233"},"PeriodicalIF":4.5000,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"One Health","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2352771425002691","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0
摘要
Q热是一种全球性的人畜共患疾病,由专性胞内细菌伯纳蒂克希菌(C. burnetii)引起。使用商用酶联免疫吸附测定试剂盒没有关于伯纳蒂胞杆菌的数据。伯纳蒂胞杆菌感染的总体血清患病率为5.9% (62/1043,95% CI 4.5-7.4)。有趣的是,C. 05)。本调查结果支持c的广泛存在,需要进一步的分子流行病学调查来了解中国青海省布氏c传播的流行病学。
Serological evidence of Q fever in Tibetan sheep in Qinghai Province, China
Q fever, caused by the obligate intracellular bacterium Coxiella burnetii (C. burnetii), is a global zoonotic disease. No data is available about C. burnetii infection in Tibetan sheep in Qinghai, China. In this study, 1043 Tibetan sheep serum samples (421 females and 622 males) were collected from 8 regions in Qinghai Province and examined for antibodies against C. burnetii using a commercial ELISA Kit. The overall seroprevalence of C. burnetii infection was 5.9 % (62/1043, 95 % CI 4.5–7.4). Interestingly, C. burnetii infection rates in Tibetan sheep showed no statistically significant correlations with age, geographical region, and gender (P > 0.05). The results of the present survey support the widespread presence of C. burnetii in Tibetan sheep in Qinghai, also providing baseline data for improving livestock management, preventing and controlling Q fever in large ruminants in the region. Further molecular epidemiological investigations are warranted to understand the epidemiology of C. burnetii transmission in Qinghai, China.
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