{"title":"分子内串联自由基环化无过渡金属合成吲哚[2,1-a]异喹啉","authors":"Zhiming Feng, Chengming Wang","doi":"10.1021/acs.joc.5c02099","DOIUrl":null,"url":null,"abstract":"Diversely functionalized indolo[2,1-<i>a</i>]isoquinolines were rapidly constructed by regioselective metal-free intramolecular tandem cyclization. Initial mechanistic studies revealed that a single electron transfer (SET) radical process was possibly involved.","PeriodicalId":57,"journal":{"name":"Journal of Organic Chemistry","volume":"86 1","pages":""},"PeriodicalIF":3.6000,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Transition-Metal-Free Synthesis of Indolo[2,1-a]isoquinolines via Intramolecular Tandem Radical Cyclization\",\"authors\":\"Zhiming Feng, Chengming Wang\",\"doi\":\"10.1021/acs.joc.5c02099\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Diversely functionalized indolo[2,1-<i>a</i>]isoquinolines were rapidly constructed by regioselective metal-free intramolecular tandem cyclization. Initial mechanistic studies revealed that a single electron transfer (SET) radical process was possibly involved.\",\"PeriodicalId\":57,\"journal\":{\"name\":\"Journal of Organic Chemistry\",\"volume\":\"86 1\",\"pages\":\"\"},\"PeriodicalIF\":3.6000,\"publicationDate\":\"2025-10-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Organic Chemistry\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://doi.org/10.1021/acs.joc.5c02099\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Organic Chemistry","FirstCategoryId":"1","ListUrlMain":"https://doi.org/10.1021/acs.joc.5c02099","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
Transition-Metal-Free Synthesis of Indolo[2,1-a]isoquinolines via Intramolecular Tandem Radical Cyclization
Diversely functionalized indolo[2,1-a]isoquinolines were rapidly constructed by regioselective metal-free intramolecular tandem cyclization. Initial mechanistic studies revealed that a single electron transfer (SET) radical process was possibly involved.
期刊介绍:
Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.