胸腔镜肺叶切除术患儿术中低温风险预测模型的构建与验证。

IF 2.9 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES
Science Progress Pub Date : 2025-10-01 Epub Date: 2025-10-09 DOI:10.1177/00368504251386310
Xiongtao Liu, Hua Lin, Yanzhen Li, Chunli Dong, Ting Wang, Xia Wang, Qiqi Yan, Ruzhong Liu, Liyan Zhao, Juan Xiao, Xiaohui Gou
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引用次数: 0

摘要

目的:建立预测模型,评估儿童胸腔镜肺叶切除术围手术期发生低温的风险,并验证其有效性。172例行胸腔镜肺叶切除术的患儿按7:3的比例随机分为训练组124例和验证组48例。该研究发现,接受胸腔镜肺叶切除术的儿童术中低温(IPH)发生率为33.1%。采用SPSS 26.0软件进行Logistic回归分析,筛选影响因素,建立风险预测模型,绘制受者-工作特征曲线。单因素分析确定麻醉-皮肤切开时间、手术室温度、湿度、基础体温、终末体温、麻醉后半小时体温为影响因素。多因素logistic回归分析显示,麻醉-皮肤切口时间(OR = 1.595)、手术室湿度(OR = 4.094)、麻醉后半小时体温(OR = 112.595)为独立预测因素。该模型具有良好的判别能力,曲线下面积(AUC)为0.989(95%可信区间为0.976 ~ 1.000),最大约登指数为0.94,灵敏度为1,特异性为0.94,截断值为0.195。Hosmer-Lemeshow检验(χ2 = 1.751, P = 0.195)和bootstrap重抽样(一致性系数= 0.947)证实了模型的拟合优度、内部一致性和稳定性。验证集结果与训练集相似,AUC为0.989 (95% CI: 0.969 ~ 1.000),灵敏度为1,特异性为0.929,校准曲线误差为0.032 (
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Construction and validation of a risk prediction model for intraoperative hypothermia in children undergoing thoracoscopic lobectomy.

To develop a predictive model to assess the risk of peri-operative hypothermia occurrence in children undergoing thoracoscopic lobectomy and validate its effectiveness. 172 children who underwent thoracoscopic lobectomy were randomly divided into a training set of 124 cases and a validation set of 48 cases in a 7:3 ratio. The study found a 33.1% incidence of intraoperative hypothermia (IPH) in children undergoing thoracoscopic lobectomy. Logistic regression analysis was performed using SPSS 26.0 to screen influencing factors, establish a risk prediction model, and draw the receiver-operating characteristic curve. Univariate analysis identified anesthesia-skin incision time, operating-room temperature, humidity, basal body temperature, end body temperature, and body temperature half an hour after anesthesia as influencing factors. Multivariate logistic regression revealed anesthesia-skin incision time (odds ratio (OR) = 1.595), operating-room humidity (OR = 4.094), and body temperature half an hour after anesthesia (OR = 112.595) as independent predictors. The nomogram model demonstrated an excellent discrimination with area under the curve (AUC) of 0.989 (95% confidence interval (CI): 0.976-1.000), maximum Youden index of 0.94, sensitivity of 1, specificity of 0.94, and cutoff value of 0.195. The Hosmer-Lemeshow test (χ2 = 1.751, P = 0.195) and bootstrap resampling (consistency coefficient = 0.947) confirmed the model's goodness of fit, internal consistency, and stability. Validation set results are similar to those in the training set, with an AUC of 0.989 (95% CI: 0.969-1.000), a sensitivity of 1, a specificity of 0.929, and a calibration curve error of 0.032 (<0.05), indicating high predictive accuracy. These findings suggest nomogram is a robust tool for predicting IPH in the pediatric thoracoscopic lobectomy.

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来源期刊
Science Progress
Science Progress Multidisciplinary-Multidisciplinary
CiteScore
3.80
自引率
0.00%
发文量
119
期刊介绍: Science Progress has for over 100 years been a highly regarded review publication in science, technology and medicine. Its objective is to excite the readers'' interest in areas with which they may not be fully familiar but which could facilitate their interest, or even activity, in a cognate field.
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