抗青光眼药物的眼部不良反应管理——对加纳验光师的调查。

IF 2.5
PLOS global public health Pub Date : 2025-10-09 eCollection Date: 2025-01-01 DOI:10.1371/journal.pgph.0004251
Mohammed Abdul-Kabir, Prince Mintah, Michael Kwesi Asante, James Forson, Agnes Oppong, James Anin Odame, Gabriel Kwaku Agbeshie, Stephanie Obeng-Inkoom
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引用次数: 0

摘要

青光眼的特点是视网膜神经节细胞的慢性进行性变性,导致视野逐渐下降,对眼科保健服务提出了重大挑战。验光师在发现和治疗青光眼方面起着至关重要的作用。本研究旨在确定加纳验光师如何处理使用抗青光眼药物的患者的眼部不良反应(oadr)。对139名持证验光师进行了横断面调查,采用预测试的半结构化问卷。收集的数据包括社会人口统计学特征、报告的不良反应以及对报告或管理方案的认识。描述性和推断性统计采用SPSS 25.0版本。参与者的平均年龄为31.6±5.5岁,平均执业经验为5.6±4.5年。大多数受访者为女性(71.2%),其中36.7%在大阿克拉执业,32.0%在私人机构执业。几乎所有的参与者(92.8%)报告在年会中遇到了oadr。最常见的症状是红眼(36.0%)、刺痛(26.1%)、灼烧感(25.4%)和瘙痒(8.8%),临床症状包括结膜充血(45.5%)、泪膜缺乏(26.0%)和虹膜色素沉着改变(9.8%)。拉坦前列素(32.2%)、替马洛尔(23.7%)、曲伏前列素(17.6%)和溴莫尼定(10.2%)是最常发生这些反应的药物。验光师主要通过改用替代药物(41.0%)或调整剂量和频率(9.7%)来管理病例。然而,77.7%的受访者表示不了解现有的治疗方案,对oadr管理的信心较低(5分制平均= 2.67±0.49)。OADR报告与年龄(p = 0.616)或执业年限(p = 0.974)均无显著关联。这些发现强调,尽管oadr在青光眼治疗中很常见,但加纳的验光师往往缺乏标准化的方案,并且报告对处理此类病例缺乏信心。需要有针对性的专业发展和进修培训,以加强oadr的识别、报告和管理,最终改善患者的眼科护理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Management of ocular adverse reactions to antiglaucoma medications-Survey of optometrists in Ghana.

Glaucoma, characterized by chronic and progressive degeneration of retinal ganglion cells leading to a gradual decline in the visual field, poses a significant challenge in eye care delivery. Optometrists play a vital role in detecting and managing glaucoma. This study aims to determine how Ghanaian optometrists manage ocular adverse reactions (OADRs) in patients using antiglaucoma medications. A cross-sectional survey was conducted among 139 licensed optometrists using a pre-tested, semi-structured questionnaire. Data collected included socio-demographic characteristics, reported adverse reactions, and awareness of reporting or management protocols. Descriptive and inferential statistics were performed using SPSS version 25.0. Participants had a mean age of 31.6 ± 5.5 years and an average practice experience of 5.6 ± 4.5 years. Most respondents were female (71.2%), with 36.7% practicing in Greater Accra and 32.0% in private facilities. Nearly all participants (92.8%) reported encountering OADRs to AGMs. The most common symptoms were red eyes (36.0%), stinging (26.1%), burning sensation (25.4%), and itching (8.8%), while clinical signs included conjunctival hyperemia (45.5%), tear film deficiency (26.0%), and iris pigmentation changes (9.8%). Latanoprost (32.2%), timolol (23.7%), travoprost (17.6%), and brimonidine (10.2%) were the medications most frequently associated with these reactions. Optometrists primarily managed cases by switching to alternative medications (41.0%) or adjusting dosage and frequency (9.7%). However, 77.7% reported having no knowledge of existing protocols, and confidence in managing OADRs was moderately low (mean = 2.67 ± 0.49 on a 5-point scale). No significant association was found between OADR reporting and either age (p = 0.616) or years of practice (p = 0.974). These findings highlight that although OADRs are common in glaucoma management, optometrists in Ghana often lack standardized protocols and report low confidence in handling such cases. Targeted professional development and refresher training are needed to strengthen OADRs recognition, reporting, and management, ultimately improving patient eye care.

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