{"title":"认知参与与痴呆风险：养老院和社区居民的剂量-反应比较。","authors":"Jungjoo Lee, Junhyoung Kim","doi":"10.1177/07334648251386106","DOIUrl":null,"url":null,"abstract":"<p><p>This study examined the relationship between participation in cognitive activities (CA), the risk of Alzheimer's disease and related dementias (AD/ADRD), and the residential setting using Health and Retirement Study data from 2012 to 2020 (<i>n</i> = 18,111). A Cox proportional hazards regression model assessed risk factors. Findings revealed that residential setting significantly predicted dementia risk. Older adults living in nursing homes were 3.57 times more likely to develop AD/ADRD than those residing in the community (95% CI [2.23, 5.07]). Although both groups showed reduced risk with increased CA participation, community dwellers experienced a 12% risk reduction compared to only 2% among nursing home residents, even when both participated in cognitive activities three to four times per week. These results underscore the dual importance of engaging in cognitive activities and considering environmental context in mitigating AD/ADRD risk among older adults.</p>","PeriodicalId":47970,"journal":{"name":"Journal of Applied Gerontology","volume":" ","pages":"7334648251386106"},"PeriodicalIF":2.0000,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cognitive Engagement and Dementia Risk: A Dose-Response Comparison of Nursing Home and Community Residents.\",\"authors\":\"Jungjoo Lee, Junhyoung Kim\",\"doi\":\"10.1177/07334648251386106\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This study examined the relationship between participation in cognitive activities (CA), the risk of Alzheimer's disease and related dementias (AD/ADRD), and the residential setting using Health and Retirement Study data from 2012 to 2020 (<i>n</i> = 18,111). A Cox proportional hazards regression model assessed risk factors. Findings revealed that residential setting significantly predicted dementia risk. Older adults living in nursing homes were 3.57 times more likely to develop AD/ADRD than those residing in the community (95% CI [2.23, 5.07]). Although both groups showed reduced risk with increased CA participation, community dwellers experienced a 12% risk reduction compared to only 2% among nursing home residents, even when both participated in cognitive activities three to four times per week. These results underscore the dual importance of engaging in cognitive activities and considering environmental context in mitigating AD/ADRD risk among older adults.</p>\",\"PeriodicalId\":47970,\"journal\":{\"name\":\"Journal of Applied Gerontology\",\"volume\":\" \",\"pages\":\"7334648251386106\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2025-10-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Applied Gerontology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/07334648251386106\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"GERONTOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Applied Gerontology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/07334648251386106","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GERONTOLOGY","Score":null,"Total":0}
Cognitive Engagement and Dementia Risk: A Dose-Response Comparison of Nursing Home and Community Residents.
This study examined the relationship between participation in cognitive activities (CA), the risk of Alzheimer's disease and related dementias (AD/ADRD), and the residential setting using Health and Retirement Study data from 2012 to 2020 (n = 18,111). A Cox proportional hazards regression model assessed risk factors. Findings revealed that residential setting significantly predicted dementia risk. Older adults living in nursing homes were 3.57 times more likely to develop AD/ADRD than those residing in the community (95% CI [2.23, 5.07]). Although both groups showed reduced risk with increased CA participation, community dwellers experienced a 12% risk reduction compared to only 2% among nursing home residents, even when both participated in cognitive activities three to four times per week. These results underscore the dual importance of engaging in cognitive activities and considering environmental context in mitigating AD/ADRD risk among older adults.
期刊介绍：
The Journal of Applied Gerontology (JAG) is the official journal of the Southern Gerontological Society. It features articles that focus on research applications intended to improve the quality of life of older persons or to enhance our understanding of age-related issues that will eventually lead to such outcomes. We construe application broadly and encourage contributions across a range of applications toward those foci, including interventions, methodology, policy, and theory. Manuscripts from all disciplines represented in gerontology are welcome. Because the circulation and intended audience of JAG is global, contributions from international authors are encouraged.
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