{"title":"1990年至2021年全球、区域和国家老年人精神障碍和物质使用障碍负担:系统分析和未来趋势预测研究","authors":"Yitian Gao, Wanqiong Zhou, Qiuyi Wang, Qianyi Zhai, Lanshu Zhou","doi":"10.3389/fpsyt.2025.1638646","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>As the global population ages, mental health has become a major public health issue affecting healthy aging. To estimate the burden, trends, and inequalities of mental disorders and substance use disorders (SUDs) among older adults aged ≥60 years at the global, regional, and national levels from 1990 to 2021.</p><p><strong>Methods: </strong>Data from the Global Burden of Disease Study 2021. The study focused on the burden of mental health conditions, analyzing mental disorders and SUDs prevalence, years lived with disability (YLDs), and average annual percentage change (AAPC), encompassing eight age groups (60-64 years, 65-69 years, 70-74 years, 75-79 years, 80-84 years, 85-89 years, 90-94 years, ≥95 years) for both men and women.</p><p><strong>Results: </strong>Globally in 2021, 1.09 billion individuals aged ≥60 years included 161.3 million (14.8%) with mental disorders and 19.2 million (1.8%) with SUDs. Mental disorders accounted for 22.8 million YLDs versus 2.10 million from SUDs in this population. From 1990 to 2021, age standardized prevalence of mental disorders increased by 3.7%, while SUDs declined by 8.7%, with lower SDI levels correlating with higher YLDs burdens overall. Over the next fifteen years, projections indicating stagnant trends in SUDs alongside slight declines in mental disorders highlight persistent unmet needs.</p><p><strong>Discussion: </strong>Global population aging demands heightened prioritization of mental healthcare for older adults. Today, mental and substance use disorders persist as major contributors to disease burden in this population. Our findings call for equitable mental resource allocation, age-adapted diagnostic tools, and policies targeting late-life psychosocial vulnerabilities.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1638646"},"PeriodicalIF":3.2000,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12504471/pdf/","citationCount":"0","resultStr":"{\"title\":\"Global, regional, and national burden of mental disorders and substance use disorders in older adults from 1990 to 2021: a systematic analysis and future trend prediction study.\",\"authors\":\"Yitian Gao, Wanqiong Zhou, Qiuyi Wang, Qianyi Zhai, Lanshu Zhou\",\"doi\":\"10.3389/fpsyt.2025.1638646\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>As the global population ages, mental health has become a major public health issue affecting healthy aging. To estimate the burden, trends, and inequalities of mental disorders and substance use disorders (SUDs) among older adults aged ≥60 years at the global, regional, and national levels from 1990 to 2021.</p><p><strong>Methods: </strong>Data from the Global Burden of Disease Study 2021. The study focused on the burden of mental health conditions, analyzing mental disorders and SUDs prevalence, years lived with disability (YLDs), and average annual percentage change (AAPC), encompassing eight age groups (60-64 years, 65-69 years, 70-74 years, 75-79 years, 80-84 years, 85-89 years, 90-94 years, ≥95 years) for both men and women.</p><p><strong>Results: </strong>Globally in 2021, 1.09 billion individuals aged ≥60 years included 161.3 million (14.8%) with mental disorders and 19.2 million (1.8%) with SUDs. Mental disorders accounted for 22.8 million YLDs versus 2.10 million from SUDs in this population. From 1990 to 2021, age standardized prevalence of mental disorders increased by 3.7%, while SUDs declined by 8.7%, with lower SDI levels correlating with higher YLDs burdens overall. Over the next fifteen years, projections indicating stagnant trends in SUDs alongside slight declines in mental disorders highlight persistent unmet needs.</p><p><strong>Discussion: </strong>Global population aging demands heightened prioritization of mental healthcare for older adults. Today, mental and substance use disorders persist as major contributors to disease burden in this population. Our findings call for equitable mental resource allocation, age-adapted diagnostic tools, and policies targeting late-life psychosocial vulnerabilities.</p>\",\"PeriodicalId\":12605,\"journal\":{\"name\":\"Frontiers in Psychiatry\",\"volume\":\"16 \",\"pages\":\"1638646\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2025-09-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12504471/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Frontiers in Psychiatry\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3389/fpsyt.2025.1638646\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"PSYCHIATRY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Psychiatry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3389/fpsyt.2025.1638646","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"PSYCHIATRY","Score":null,"Total":0}
Global, regional, and national burden of mental disorders and substance use disorders in older adults from 1990 to 2021: a systematic analysis and future trend prediction study.
Introduction: As the global population ages, mental health has become a major public health issue affecting healthy aging. To estimate the burden, trends, and inequalities of mental disorders and substance use disorders (SUDs) among older adults aged ≥60 years at the global, regional, and national levels from 1990 to 2021.
Methods: Data from the Global Burden of Disease Study 2021. The study focused on the burden of mental health conditions, analyzing mental disorders and SUDs prevalence, years lived with disability (YLDs), and average annual percentage change (AAPC), encompassing eight age groups (60-64 years, 65-69 years, 70-74 years, 75-79 years, 80-84 years, 85-89 years, 90-94 years, ≥95 years) for both men and women.
Results: Globally in 2021, 1.09 billion individuals aged ≥60 years included 161.3 million (14.8%) with mental disorders and 19.2 million (1.8%) with SUDs. Mental disorders accounted for 22.8 million YLDs versus 2.10 million from SUDs in this population. From 1990 to 2021, age standardized prevalence of mental disorders increased by 3.7%, while SUDs declined by 8.7%, with lower SDI levels correlating with higher YLDs burdens overall. Over the next fifteen years, projections indicating stagnant trends in SUDs alongside slight declines in mental disorders highlight persistent unmet needs.
Discussion: Global population aging demands heightened prioritization of mental healthcare for older adults. Today, mental and substance use disorders persist as major contributors to disease burden in this population. Our findings call for equitable mental resource allocation, age-adapted diagnostic tools, and policies targeting late-life psychosocial vulnerabilities.
期刊介绍:
Frontiers in Psychiatry publishes rigorously peer-reviewed research across a wide spectrum of translational, basic and clinical research. Field Chief Editor Stefan Borgwardt at the University of Basel is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.
The journal''s mission is to use translational approaches to improve therapeutic options for mental illness and consequently to improve patient treatment outcomes.