广泛耐药淋病奈瑟菌在德国的本土传播，2025。

IF 7.8 2区医学 Q1 INFECTIOUS DISEASES

Eurosurveillance Pub Date : 2025-10-01 DOI:10.2807/1560-7917.ES.2025.30.40.2500738

Regina Selb, Hana Tlapák, Kathleen Klaper, Susanne Buder, Klaus Jansen, Dagmar Heuer

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引用次数: 0

摘要

我们报告了2025年在德国确诊的4例本土传播淋病病例，淋病奈瑟菌分离株表现出高水平的阿奇霉素和头孢克肟耐药性。头孢曲松有2例敏感，2例耐药，后者为广泛耐药（XDR-NG）。所有病例都是异性恋男性，年龄在60多岁至60多岁之间。3株分离株为MLST ST18091，具有花叶式penA-60.001等位基因和23S rRNA A2045G突变，与2024年在英国检测到的XDR-NG相关。

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Autochthonous transmission of extensively drug-resistant Neisseria gonorrhoeae in Germany, 2025.

We report four confirmed autochthonously transmitted gonorrhoea cases in Germany in 2025, with Neisseria gonorrhoeae isolates exhibiting high-level azithromycin and cefixime resistance. Regarding ceftriaxone, isolates were susceptible for two cases and resistant for two, rendering the later extensively drug-resistant (XDR-NG). Cases, all heterosexual males, were in their late teens to mid-60s. Three isolates were MLST ST18091, with the mosaic penA-60.001 allele and the 23S rRNA A2045G mutation and were related to an XDR-NG detected in the United Kingdom in 2024.

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来源期刊

Eurosurveillance INFECTIOUS DISEASES-

CiteScore

32.70

自引率

2.10%

发文量

430

审稿时长

3-8 weeks

期刊介绍： Eurosurveillance is a European peer-reviewed journal focusing on the epidemiology, surveillance, prevention, and control of communicable diseases relevant to Europe.It is a weekly online journal, with 50 issues per year published on Thursdays. The journal includes short rapid communications, in-depth research articles, surveillance reports, reviews, and perspective papers. It excels in timely publication of authoritative papers on ongoing outbreaks or other public health events. Under special circumstances when current events need to be urgently communicated to readers for rapid public health action, e-alerts can be released outside of the regular publishing schedule. Additionally, topical compilations and special issues may be provided in PDF format.