当神经胶质组织游离:三倍体胎儿胸膜下异位的独特病例报告和文献回顾。

IF 3.1 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Frontiers in Medicine Pub Date : 2025-09-24 eCollection Date: 2025-01-01 DOI:10.3389/fmed.2025.1598144
Viktor Procházka, Valeria Skopelidou, Patricie Delongová, Pavel Hurník, Richard Špaček, David Matura, Jan Pavlíček, Andrea Gřegořová, Jana Vaculová, Jozef Škarda
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引用次数: 0

摘要

神经胶质组织异位发生是一种非常罕见的现象,其发病机制尚不清楚,通常表现为中枢神经系统外的病变。我们报告一个独特的情况下,异位神经胶质组织鉴定的胎儿在14 周流产的胸腔由于可疑的Dandy-Walker畸形。胎儿表现出胸膜下神经胶质组织生长,并伴有疑似Dandy-Walker畸形和室间隔缺损。虽然血管栓塞、误吸和异常迁移等理论试图解释这些现象,但确切的病因仍然难以捉摸。我们的病例表明三倍体和神经胶质异位之间存在潜在的联系,支持异常迁移和分化理论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
When neuroglial tissue wanders: a unique case report of subpleural heterotopia in a triploid foetus and review of the literature.

Heterotopic occurrence of neuroglial tissue is an exceedingly rare phenomenon with unclear pathogenesis, often presenting as lesions outside the central nervous system (CNS). We report a unique case of heterotopic neuroglial tissue identified in the thoracic cavity of a fetus aborted at 14 weeks due to a suspected Dandy-Walker malformation. The fetus exhibited neuroglial tissue growth subpleurally, alongside a suspected Dandy-Walker malformation and ventricular septal defect. While theories such as vascular embolisation, aspiration, and aberrant migration attempt to explain such occurrences, the exact etiology remains elusive. Our case suggests a potential association between triploidy and neuroglial heterotopia, supporting the aberrant migration and differentiation theory.

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来源期刊
Frontiers in Medicine
Frontiers in Medicine Medicine-General Medicine
CiteScore
5.10
自引率
5.10%
发文量
3710
审稿时长
12 weeks
期刊介绍: Frontiers in Medicine publishes rigorously peer-reviewed research linking basic research to clinical practice and patient care, as well as translating scientific advances into new therapies and diagnostic tools. Led by an outstanding Editorial Board of international experts, this multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. In addition to papers that provide a link between basic research and clinical practice, a particular emphasis is given to studies that are directly relevant to patient care. In this spirit, the journal publishes the latest research results and medical knowledge that facilitate the translation of scientific advances into new therapies or diagnostic tools. The full listing of the Specialty Sections represented by Frontiers in Medicine is as listed below. As well as the established medical disciplines, Frontiers in Medicine is launching new sections that together will facilitate - the use of patient-reported outcomes under real world conditions - the exploitation of big data and the use of novel information and communication tools in the assessment of new medicines - the scientific bases for guidelines and decisions from regulatory authorities - access to medicinal products and medical devices worldwide - addressing the grand health challenges around the world
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