Lijuan Xu, Juan Gu, Wenqing Ye, Xinyao Zhang, Yin Zhao, Tao Zhou, Jialing Han, Ruiyi Ren, Yuanbo Liang
{"title":"青光眼患者穿透性小管成形术后早期一过性眼压升高的发生率及危险因素。","authors":"Lijuan Xu, Juan Gu, Wenqing Ye, Xinyao Zhang, Yin Zhao, Tao Zhou, Jialing Han, Ruiyi Ren, Yuanbo Liang","doi":"10.1186/s12886-025-04399-9","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>This study aimed to evaluate the incidence and risk factors for early transient intraocular pressure (IOP) elevation after penetrating canaloplasty (PCP) in patients with primary open-angle glaucoma (POAG), primary angle-closure glaucoma (PACG) and secondary glaucoma (SG).</p><p><strong>Methods: </strong>This retrospective study included 198 eyes of 198 patients with glaucoma. Participants were classified as normal IOP, early transient high IOP (E-HIOP [Tst]), early persistent IOP elevation, late transient high IOP, and late persistent IOP elevation, based on the period and persistence of postoperative IOP elevation.</p><p><strong>Results: </strong>E-HIOP (Tst) developed in 34.8%, 33.3%, and 40.9% of eyes with POAG, PACG, and SG, respectively. In comparison with normal IOP group, we observed the following variations in E-HIOP (Tst) cohorts: 8 - 10 years younger in patients with POAG and PACG; higher prevalence of hyphema (45.5% vs. 20.5%) in POAG; higher baseline IOP in PACG and SG (7 - 8 mmHg); higher preoperative IOP maximum (IOP<sub>pre-max</sub>) in SG (all p < 0.05). Higher IOP<sub>pre-max</sub> was a risk factor for E-HIOP (Tst) in PACG and SG (p < 0.05).</p><p><strong>Conclusions: </strong>Nearly 30 - 40% of eyes developed E-HIOP (Tst) after PCP. E-HIOP (Tst) tended to develop in younger participants and those with higher preoperative IOP. A higher IOP<sub>pre-max</sub> was a risk factor for E-HIOP (Tst) in PACG and SG.</p>","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"559"},"PeriodicalIF":1.7000,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12512409/pdf/","citationCount":"0","resultStr":"{\"title\":\"Incidence and risk factors for early transient intraocular pressure elevation after penetrating canaloplasty in patients with glaucoma.\",\"authors\":\"Lijuan Xu, Juan Gu, Wenqing Ye, Xinyao Zhang, Yin Zhao, Tao Zhou, Jialing Han, Ruiyi Ren, Yuanbo Liang\",\"doi\":\"10.1186/s12886-025-04399-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>This study aimed to evaluate the incidence and risk factors for early transient intraocular pressure (IOP) elevation after penetrating canaloplasty (PCP) in patients with primary open-angle glaucoma (POAG), primary angle-closure glaucoma (PACG) and secondary glaucoma (SG).</p><p><strong>Methods: </strong>This retrospective study included 198 eyes of 198 patients with glaucoma. Participants were classified as normal IOP, early transient high IOP (E-HIOP [Tst]), early persistent IOP elevation, late transient high IOP, and late persistent IOP elevation, based on the period and persistence of postoperative IOP elevation.</p><p><strong>Results: </strong>E-HIOP (Tst) developed in 34.8%, 33.3%, and 40.9% of eyes with POAG, PACG, and SG, respectively. In comparison with normal IOP group, we observed the following variations in E-HIOP (Tst) cohorts: 8 - 10 years younger in patients with POAG and PACG; higher prevalence of hyphema (45.5% vs. 20.5%) in POAG; higher baseline IOP in PACG and SG (7 - 8 mmHg); higher preoperative IOP maximum (IOP<sub>pre-max</sub>) in SG (all p < 0.05). Higher IOP<sub>pre-max</sub> was a risk factor for E-HIOP (Tst) in PACG and SG (p < 0.05).</p><p><strong>Conclusions: </strong>Nearly 30 - 40% of eyes developed E-HIOP (Tst) after PCP. E-HIOP (Tst) tended to develop in younger participants and those with higher preoperative IOP. A higher IOP<sub>pre-max</sub> was a risk factor for E-HIOP (Tst) in PACG and SG.</p>\",\"PeriodicalId\":9058,\"journal\":{\"name\":\"BMC Ophthalmology\",\"volume\":\"25 1\",\"pages\":\"559\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-10-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12512409/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMC Ophthalmology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s12886-025-04399-9\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Ophthalmology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12886-025-04399-9","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Incidence and risk factors for early transient intraocular pressure elevation after penetrating canaloplasty in patients with glaucoma.
Background: This study aimed to evaluate the incidence and risk factors for early transient intraocular pressure (IOP) elevation after penetrating canaloplasty (PCP) in patients with primary open-angle glaucoma (POAG), primary angle-closure glaucoma (PACG) and secondary glaucoma (SG).
Methods: This retrospective study included 198 eyes of 198 patients with glaucoma. Participants were classified as normal IOP, early transient high IOP (E-HIOP [Tst]), early persistent IOP elevation, late transient high IOP, and late persistent IOP elevation, based on the period and persistence of postoperative IOP elevation.
Results: E-HIOP (Tst) developed in 34.8%, 33.3%, and 40.9% of eyes with POAG, PACG, and SG, respectively. In comparison with normal IOP group, we observed the following variations in E-HIOP (Tst) cohorts: 8 - 10 years younger in patients with POAG and PACG; higher prevalence of hyphema (45.5% vs. 20.5%) in POAG; higher baseline IOP in PACG and SG (7 - 8 mmHg); higher preoperative IOP maximum (IOPpre-max) in SG (all p < 0.05). Higher IOPpre-max was a risk factor for E-HIOP (Tst) in PACG and SG (p < 0.05).
Conclusions: Nearly 30 - 40% of eyes developed E-HIOP (Tst) after PCP. E-HIOP (Tst) tended to develop in younger participants and those with higher preoperative IOP. A higher IOPpre-max was a risk factor for E-HIOP (Tst) in PACG and SG.
期刊介绍：
BMC Ophthalmology is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of eye disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
