Robert W Motl, Petra Šilić, Trinh L T Huynh, Brenda Jeng
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The data analyses were performed using IBM SPSS Version 29.0.2.0 for the iOS platform.</p><p><strong>Results: </strong>There were similar patterns of linear worsening of scores for the MSWS-12 (F<sub>1,187</sub>=12.7, p<.001, η<sup>2</sup>=.07), T25FW (F<sub>1,187</sub>=11.5, p<.001, η<sup>2</sup>=.06), 6MW (F<sub>1,187</sub>=13.1, p<.001, η<sup>2</sup>=.08), and TUG (F<sub>1,184</sub>=10.8, p<.001, η<sup>2</sup>=.06) across the three age-groups. MSWS-12 scores had strong partial correlations with T25FW, 6MW, and TUG in the overall sample (partial r's of .59, .66, .55, respectively) and across the three age-groups, when controlling for BICAMS outcomes.</p><p><strong>Conclusions: </strong>We provide new evidence for the construct validity of MSWS-12 scores as a PROM of walking dysfunction across the adult lifespan in MS. Our results, in particular, support the application of the MSWS-12 in clinical research and practice involving older adults with MS who experience the combined effects of advanced age and MS disease progression.</p>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Validity of Scores from the 12-Item Multiple Sclerosis Walking Scale Among Young, Middle-Aged, and Older Adults with Multiple Sclerosis.\",\"authors\":\"Robert W Motl, Petra Šilić, Trinh L T Huynh, Brenda Jeng\",\"doi\":\"10.1016/j.apmr.2025.09.023\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To examine the construct validity of inferences from MSWS-12 scores as a PROM of walking dysfunction among young, middle-aged, and older adults with MS.</p><p><strong>Design: </strong>Cross-sectional, comparative research design.</p><p><strong>Setting: </strong>University research laboratory.</p><p><strong>Participants: </strong>The sample included 187 participants with MS who were categorized into young (20-39 years, n=50), middle-aged (40-59 years, n=83), and older (60-79 years, n=54) adult age-groups.</p><p><strong>Intervention: </strong>N/A MAIN OUTCOME MEASURES: The participants completed the MSWS-12; the Timed 25-Foot Walk (T25FW), Six-Minute Walk (6MW), and Timed-Up-and-Go (TUG); and Brief International Cognitive Assessment for MS (BICAMS). The data analyses were performed using IBM SPSS Version 29.0.2.0 for the iOS platform.</p><p><strong>Results: </strong>There were similar patterns of linear worsening of scores for the MSWS-12 (F<sub>1,187</sub>=12.7, p<.001, η<sup>2</sup>=.07), T25FW (F<sub>1,187</sub>=11.5, p<.001, η<sup>2</sup>=.06), 6MW (F<sub>1,187</sub>=13.1, p<.001, η<sup>2</sup>=.08), and TUG (F<sub>1,184</sub>=10.8, p<.001, η<sup>2</sup>=.06) across the three age-groups. MSWS-12 scores had strong partial correlations with T25FW, 6MW, and TUG in the overall sample (partial r's of .59, .66, .55, respectively) and across the three age-groups, when controlling for BICAMS outcomes.</p><p><strong>Conclusions: </strong>We provide new evidence for the construct validity of MSWS-12 scores as a PROM of walking dysfunction across the adult lifespan in MS. 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引用次数: 0
摘要
目的：检验MSWS-12评分作为青年、中年和老年人多发性硬化症患者行走功能障碍的预测指标的结构效度。设计：横断面比较研究设计。环境：大学研究实验室。参与者：样本包括187名多发性硬化症患者，分为青年（20-39岁，n=50）、中年（40-59岁，n=83）和老年（60-79岁，n=54）成人年龄组。主要观察指标：参与者完成MSWS-12；计时25英尺步行（T25FW）、6分钟步行（6MW）和计时起身（TUG）；以及国际多发性硬化症认知评估（BICAMS）。数据分析采用IBM SPSS Version 29.0.2.0 for iOS平台。结果：MSWS-12 （f1187 =12.7, p2=.07）、T25FW （f1187 =11.5, p2=.06）、6MW （f1187 =13.1, p2=.08）和TUG （f1184 =10.8, p2=.06）评分在三个年龄组中呈相似的线性恶化模式。在整个样本中，MSWS-12分数与T25FW、6MW和TUG有很强的偏相关(偏r值为。59岁。66年,。在控制BICAMS结果时，在三个年龄组中分别为55例。结论：我们为mws -12评分作为MS成年期行走功能障碍的结构有效性提供了新的证据。我们的研究结果特别支持mws -12在临床研究和实践中的应用，这些临床研究和实践涉及老年MS患者，他们经历了高龄和MS疾病进展的综合影响。
Validity of Scores from the 12-Item Multiple Sclerosis Walking Scale Among Young, Middle-Aged, and Older Adults with Multiple Sclerosis.
Objective: To examine the construct validity of inferences from MSWS-12 scores as a PROM of walking dysfunction among young, middle-aged, and older adults with MS.
Design: Cross-sectional, comparative research design.
Setting: University research laboratory.
Participants: The sample included 187 participants with MS who were categorized into young (20-39 years, n=50), middle-aged (40-59 years, n=83), and older (60-79 years, n=54) adult age-groups.
Intervention: N/A MAIN OUTCOME MEASURES: The participants completed the MSWS-12; the Timed 25-Foot Walk (T25FW), Six-Minute Walk (6MW), and Timed-Up-and-Go (TUG); and Brief International Cognitive Assessment for MS (BICAMS). The data analyses were performed using IBM SPSS Version 29.0.2.0 for the iOS platform.
Results: There were similar patterns of linear worsening of scores for the MSWS-12 (F1,187=12.7, p<.001, η2=.07), T25FW (F1,187=11.5, p<.001, η2=.06), 6MW (F1,187=13.1, p<.001, η2=.08), and TUG (F1,184=10.8, p<.001, η2=.06) across the three age-groups. MSWS-12 scores had strong partial correlations with T25FW, 6MW, and TUG in the overall sample (partial r's of .59, .66, .55, respectively) and across the three age-groups, when controlling for BICAMS outcomes.
Conclusions: We provide new evidence for the construct validity of MSWS-12 scores as a PROM of walking dysfunction across the adult lifespan in MS. Our results, in particular, support the application of the MSWS-12 in clinical research and practice involving older adults with MS who experience the combined effects of advanced age and MS disease progression.
期刊介绍：
The Archives of Physical Medicine and Rehabilitation publishes original, peer-reviewed research and clinical reports on important trends and developments in physical medicine and rehabilitation and related fields. This international journal brings researchers and clinicians authoritative information on the therapeutic utilization of physical, behavioral and pharmaceutical agents in providing comprehensive care for individuals with chronic illness and disabilities.
Archives began publication in 1920, publishes monthly, and is the official journal of the American Congress of Rehabilitation Medicine. Its papers are cited more often than any other rehabilitation journal.
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