血管内动脉瘤修复后主动脉夹层-系统回顾和管理算法。

IF 0.7
Angus Pegler, Yogeesan Sivakumaran
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引用次数: 0

摘要

背景:血管内动脉瘤修复(EVAR)后主动脉夹层可能是医源性的,也可能是新生事件。本研究旨在系统回顾EVAR后的所有解剖病例,以确定每种情况的具体并发症,并根据临床表现制定管理算法。方法综合检索MEDLINE、Embase和CENTRAL数据库中与EVAR或开窗/分支EVAR (F/BrEVAR)术后解剖相关的所有研究。收集的数据包括时间(区分医源性事件和新生事件)、进入撕裂位置、涉及的内移植物、并发症、处理和随后的结果。由于可用数据有限,收集描述性数据并根据解剖类型和时间对结果进行比较。使用病例报告的标准化工具评估偏倚风险。结果纳入37项研究46例患者。并发症包括移植物压迫(52.2%)、内漏(15.2%)和破裂(13.0%)。与没有近端固定的内移植物(69.2%)相比,有近端固定的内移植物(41.9%)发生压迫的可能性较小。EVAR后A型夹层需行心脏手术,死亡率高(20.0%)。B型夹层2例,F/BrEVAR术中确诊,1例死亡。8例患者在4周内确诊,死亡率为25.8%,移植物压迫率(58.1%)、内漏率(16.1%)和破裂率(19.4%)较高。结论EVAR后主动脉夹层可引起血管压迫、血管内漏或破裂,死亡率高。并发症在A型夹层和B型夹层晚期更为常见。早期B型夹层可能需要药物治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Aortic Dissection Following Endovascular Aneurysm Repair - A Systematic Review and Management Algorithm.

BackgroundAortic dissection following endovascular aneurysm repair (EVAR) may be iatrogenic or a de-novo event. This study aims to systematically review all cases of dissection following EVAR to identify complications specific to each scenario and develop a management algorithm depending on the clinical presentation.MethodsA comprehensive literature search of MEDLINE, Embase, and CENTRAL databases was performed for all studies relating to dissection following EVAR or fenestrated/branched EVAR (F/BrEVAR). Data collected included timing (differentiating iatrogenic and de-novo events), entry tear location, endograft involved, complications, management, and subsequent outcomes. Due to limited data availability, descriptive data was collected and outcomes compared depending on dissection type and timing. Risk of bias was assessed using a standardised tool for case reports.Results46 patients in 37 studies were included. Complications included endograft compression (52.2%), endoleak (15.2%), and rupture (13.0%). Compression was less likely in endografts with proximal fixation (41.9%), compared to those without (69.2%). Type A dissection after EVAR required cardiac surgery with a high mortality (20.0%). In Type B dissection, 2 cases were diagnosed intra-operatively during F/BrEVAR, 1 died. 8 were diagnosed <4 weeks post-operatively, all managed medically with no complications or mortality. 31 were diagnosed >4 weeks, with mortality of 25.8% and high rates of endograft compression (58.1%), endoleak (16.1%), and rupture (19.4%).ConclusionAortic dissection following EVAR may cause endograft compression, endoleak, or rupture, with significant mortality. Complications are more frequent following Type A dissection and late Type B dissection. Early Type B dissection may be amenable to medical management.

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