多点阻抗控制射频消融鼻后神经治疗慢性鼻炎后两年的临床疗效。

IF 0.7
David M Yen, Greg E Davis, Randall A Ow, Ellen M O'Malley, Anthony G Del Signore
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引用次数: 0

摘要

目的:慢性鼻炎会严重影响患者的生活质量。我们报告了使用一种新型多点、阻抗控制的射频消融设备治疗后患者的2年预后。方法:一项前瞻性,多中心,单臂临床研究后鼻神经消融治疗成人慢性鼻炎。疗效评估包括鼻症状总评分(rTNSS)、鼻后滴涕、咳嗽、咽鼓管功能障碍问卷-7 (ETDQ-7)、鼻塞症状评估(NOSE)和迷你鼻结膜炎生活质量问卷(mini-RQLQ)。结果:80名参与者中有75名(94%)完成了2年的随访。从rTNSS(-4.3)、鼻后滴涕(-0.9)、咳嗽(-0.7)、ETDQ-7(-1.1)、NOSE(-31.7)和迷你rqlq(-1.7)的平均变化来看,在鼻炎症状、鼻后滴涕、咳嗽、耳部症状和生活质量方面均有统计学上显著的改善。结论:数据显示多点、阻抗控制、射频消融装置治疗慢性鼻炎的长期疗效和安全性是一致的。通过2年的随访,观察到鼻炎症状、后滴鼻、咳嗽、耳部症状和生活质量有显著改善。研究注册:www.Clinicaltrials: gov唯一标识符NCT05591989。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Two-Year Clinical Outcomes After Multipoint Impedance-Controlled Radiofrequency Ablation of the Posterior Nasal Nerve for Treatment of Chronic Rhinitis.

Objective: A person's quality of life can be deeply impacted by chronic rhinitis. We report 2-year outcomes in patients after treatment using a novel, multipoint, impedance-controlled, radiofrequency ablation device.

Methods: A prospective, multicenter, single-arm clinical study of posterior nasal nerve ablation in adults with chronic rhinitis. Efficacy assessments included the reflective total nasal symptom score (rTNSS), postnasal drip, cough, Eustachian Tube Dysfunction Questionnaire-7 (ETDQ-7), nasal obstruction symptom evaluation (NOSE), and mini-Rhinoconjunctivitis Quality of Life Questionnaire (mini-RQLQ).

Results: Seventy-five of 80 (94%) participants completed 2-year follow-up. Statistically significant improvements were observed in rhinitis symptoms, postnasal drip, cough, ear symptoms, and quality of life as evidenced by the mean change in rTNSS (-4.3), postnasal drip (-0.9), cough (-0.7), ETDQ-7 (-1.1), NOSE (-31.7), and mini-RQLQ (-1.7; P < .0001 for all). Allergic and nonallergic rhinitis subgroups demonstrated similar, significant improvement. No serious related adverse events were reported between the 9-month and 2-year follow-ups.

Conclusions: The data demonstrate consistent long-term efficacy and safety of a multipoint, impedance-controlled, radiofrequency ablation device for the treatment of chronic rhinitis. Significant improvements were observed in rhinitis symptoms, postnasal drip, cough, ear symptoms, and quality of life through 2-year follow-up.

Study registration: www.

Clinicaltrials: gov. Unique identifier NCT05591989.

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