Lucas Lima Galvão, Douglas de Assis Teles Santos, Claudio Andre Barbosa de Lira, Jair Sindra Virtuoso Júnior, Sheilla Tribess, Ricardo Borges Viana, Anne Sulivan Lopes da Silva Reis, Katja Weiss, Beat Knechtle, Rodrigo Luiz Vancini
{"title":"ELSIA研究中老年人死亡风险的决定因素:一项前瞻性队列研究。","authors":"Lucas Lima Galvão, Douglas de Assis Teles Santos, Claudio Andre Barbosa de Lira, Jair Sindra Virtuoso Júnior, Sheilla Tribess, Ricardo Borges Viana, Anne Sulivan Lopes da Silva Reis, Katja Weiss, Beat Knechtle, Rodrigo Luiz Vancini","doi":"10.1590/1516-3180.2024.0402.R1.24032025","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>This study investigated factors that may determine longevity in older adults, aiming to prolong their life expectancy and improve projections from before the coronavirus disease 2019 pandemic.</p><p><strong>Objective: </strong>To identify risk factors for mortality in older Brazilian adults.</p><p><strong>Design and setting: </strong>A prospective cohort study, part of the Estudo Longitudinal de Saúde do Idoso de Alcobaça.</p><p><strong>Methods: </strong>This study included 332 older adults of both sexes who were followed up for over five years (2015-2020). Vital status was determined via telephone follow-up, information provided by family members, and death certificates. To identify the sociodemographic, health, functional, and behavioral factors associated with mortality risk among older adults, Cox proportional hazards regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs).</p><p><strong>Results: </strong>The risk factors for mortality among older adults included the number of people living with them (HR = 1.22; 95%CI = 1.07-1.38) and the number of prescribed drugs (HR = 1.15; 95%CI = 1.00-1.32). Factors associated with a lower risk of mortality were greater time spent in physical activity (HR = 0.99; 95%CI = 0.90-0.99) and greater hip circumference (HR = 0.95; 95%CI = 0.31-0.99).</p><p><strong>Conclusions: </strong>Sociodemographic, health, functional, and behavioral factors are determinants of mortality risk among older adults. Regular screening of the older adult population should be conducted to assess their general health status, allowing for more appropriate interventions to increase their quality of life and improve aging.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 5","pages":"e2024402"},"PeriodicalIF":1.6000,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12503416/pdf/","citationCount":"0","resultStr":"{\"title\":\"Determinants of mortality risk in older adults from the ELSIA study: a prospective cohort study.\",\"authors\":\"Lucas Lima Galvão, Douglas de Assis Teles Santos, Claudio Andre Barbosa de Lira, Jair Sindra Virtuoso Júnior, Sheilla Tribess, Ricardo Borges Viana, Anne Sulivan Lopes da Silva Reis, Katja Weiss, Beat Knechtle, Rodrigo Luiz Vancini\",\"doi\":\"10.1590/1516-3180.2024.0402.R1.24032025\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>This study investigated factors that may determine longevity in older adults, aiming to prolong their life expectancy and improve projections from before the coronavirus disease 2019 pandemic.</p><p><strong>Objective: </strong>To identify risk factors for mortality in older Brazilian adults.</p><p><strong>Design and setting: </strong>A prospective cohort study, part of the Estudo Longitudinal de Saúde do Idoso de Alcobaça.</p><p><strong>Methods: </strong>This study included 332 older adults of both sexes who were followed up for over five years (2015-2020). Vital status was determined via telephone follow-up, information provided by family members, and death certificates. To identify the sociodemographic, health, functional, and behavioral factors associated with mortality risk among older adults, Cox proportional hazards regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs).</p><p><strong>Results: </strong>The risk factors for mortality among older adults included the number of people living with them (HR = 1.22; 95%CI = 1.07-1.38) and the number of prescribed drugs (HR = 1.15; 95%CI = 1.00-1.32). Factors associated with a lower risk of mortality were greater time spent in physical activity (HR = 0.99; 95%CI = 0.90-0.99) and greater hip circumference (HR = 0.95; 95%CI = 0.31-0.99).</p><p><strong>Conclusions: </strong>Sociodemographic, health, functional, and behavioral factors are determinants of mortality risk among older adults. Regular screening of the older adult population should be conducted to assess their general health status, allowing for more appropriate interventions to increase their quality of life and improve aging.</p>\",\"PeriodicalId\":49574,\"journal\":{\"name\":\"Sao Paulo Medical Journal\",\"volume\":\"143 5\",\"pages\":\"e2024402\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2025-10-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12503416/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Sao Paulo Medical Journal\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1590/1516-3180.2024.0402.R1.24032025\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sao Paulo Medical Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1590/1516-3180.2024.0402.R1.24032025","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Determinants of mortality risk in older adults from the ELSIA study: a prospective cohort study.
Background: This study investigated factors that may determine longevity in older adults, aiming to prolong their life expectancy and improve projections from before the coronavirus disease 2019 pandemic.
Objective: To identify risk factors for mortality in older Brazilian adults.
Design and setting: A prospective cohort study, part of the Estudo Longitudinal de Saúde do Idoso de Alcobaça.
Methods: This study included 332 older adults of both sexes who were followed up for over five years (2015-2020). Vital status was determined via telephone follow-up, information provided by family members, and death certificates. To identify the sociodemographic, health, functional, and behavioral factors associated with mortality risk among older adults, Cox proportional hazards regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs).
Results: The risk factors for mortality among older adults included the number of people living with them (HR = 1.22; 95%CI = 1.07-1.38) and the number of prescribed drugs (HR = 1.15; 95%CI = 1.00-1.32). Factors associated with a lower risk of mortality were greater time spent in physical activity (HR = 0.99; 95%CI = 0.90-0.99) and greater hip circumference (HR = 0.95; 95%CI = 0.31-0.99).
Conclusions: Sociodemographic, health, functional, and behavioral factors are determinants of mortality risk among older adults. Regular screening of the older adult population should be conducted to assess their general health status, allowing for more appropriate interventions to increase their quality of life and improve aging.
期刊介绍:
Published bimonthly by the Associação Paulista de Medicina, the journal accepts articles in the fields of clinical health science (internal medicine, gynecology and obstetrics, mental health, surgery, pediatrics and public health). Articles will be accepted in the form of original articles (clinical trials, cohort, case-control, prevalence, incidence, accuracy and cost-effectiveness studies and systematic reviews with or without meta-analysis), narrative reviews of the literature, case reports, short communications and letters to the editor. Papers with a commercial objective will not be accepted.