{"title":"辅助生殖技术的精子选择：我们有赢家吗？","authors":"Youjiang Li, Hao Wang, Xue Sun, Qiaodan Li, Jian Xu","doi":"10.1007/s10815-025-03684-2","DOIUrl":null,"url":null,"abstract":"<p><p>Assisted reproductive technology (ART) has emerged as a pivotal solution for human infertility, with intracytoplasmic sperm injection (ICSI) being widely adopted. The quality of sperm is critical to the outcomes of ART, and the selection of optimal sperm is essential for enhancing embryo quality. In recent years, researchers have developed various advanced sperm selection methods that simulate the natural sperm selection process occurring in the female reproductive tract. Although many studies have been conducted to identify the selection technique, many doubts and disagreements still remain. In this review, we will examine the characteristics, advantages, and limitations of both traditional and advanced sperm selection methods, evaluate their impact on sperm quality and functional parameters, as well as ART outcomes for infertile couples, and provide evidence-based recommendations for embryologists to optimize sperm selection strategies.</p>","PeriodicalId":15246,"journal":{"name":"Journal of Assisted Reproduction and Genetics","volume":" ","pages":""},"PeriodicalIF":2.7000,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sperm selection for assisted reproductive technology: do we have a winner?\",\"authors\":\"Youjiang Li, Hao Wang, Xue Sun, Qiaodan Li, Jian Xu\",\"doi\":\"10.1007/s10815-025-03684-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Assisted reproductive technology (ART) has emerged as a pivotal solution for human infertility, with intracytoplasmic sperm injection (ICSI) being widely adopted. The quality of sperm is critical to the outcomes of ART, and the selection of optimal sperm is essential for enhancing embryo quality. In recent years, researchers have developed various advanced sperm selection methods that simulate the natural sperm selection process occurring in the female reproductive tract. Although many studies have been conducted to identify the selection technique, many doubts and disagreements still remain. In this review, we will examine the characteristics, advantages, and limitations of both traditional and advanced sperm selection methods, evaluate their impact on sperm quality and functional parameters, as well as ART outcomes for infertile couples, and provide evidence-based recommendations for embryologists to optimize sperm selection strategies.</p>\",\"PeriodicalId\":15246,\"journal\":{\"name\":\"Journal of Assisted Reproduction and Genetics\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2025-10-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Assisted Reproduction and Genetics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s10815-025-03684-2\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"GENETICS & HEREDITY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Assisted Reproduction and Genetics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s10815-025-03684-2","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GENETICS & HEREDITY","Score":null,"Total":0}
Sperm selection for assisted reproductive technology: do we have a winner?
Assisted reproductive technology (ART) has emerged as a pivotal solution for human infertility, with intracytoplasmic sperm injection (ICSI) being widely adopted. The quality of sperm is critical to the outcomes of ART, and the selection of optimal sperm is essential for enhancing embryo quality. In recent years, researchers have developed various advanced sperm selection methods that simulate the natural sperm selection process occurring in the female reproductive tract. Although many studies have been conducted to identify the selection technique, many doubts and disagreements still remain. In this review, we will examine the characteristics, advantages, and limitations of both traditional and advanced sperm selection methods, evaluate their impact on sperm quality and functional parameters, as well as ART outcomes for infertile couples, and provide evidence-based recommendations for embryologists to optimize sperm selection strategies.
期刊介绍：
The Journal of Assisted Reproduction and Genetics publishes cellular, molecular, genetic, and epigenetic discoveries advancing our understanding of the biology and underlying mechanisms from gametogenesis to offspring health. Special emphasis is placed on the practice and evolution of assisted reproduction technologies (ARTs) with reference to the diagnosis and management of diseases affecting fertility. Our goal is to educate our readership in the translation of basic and clinical discoveries made from human or relevant animal models to the safe and efficacious practice of human ARTs. The scientific rigor and ethical standards embraced by the JARG editorial team ensures a broad international base of expertise guiding the marriage of contemporary clinical research paradigms with basic science discovery. JARG publishes original papers, minireviews, case reports, and opinion pieces often combined into special topic issues that will educate clinicians and scientists with interests in the mechanisms of human development that bear on the treatment of infertility and emerging innovations in human ARTs. The guiding principles of male and female reproductive health impacting pre- and post-conceptional viability and developmental potential are emphasized within the purview of human reproductive health in current and future generations of our species.
The journal is published in cooperation with the American Society for Reproductive Medicine, an organization of more than 8,000 physicians, researchers, nurses, technicians and other professionals dedicated to advancing knowledge and expertise in reproductive biology.
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