微塑料暴露对肾功能的有害影响。

IF 3.1 3区医学 Q1 MEDICINE, GENERAL & INTERNAL

Frontiers in Medicine Pub Date : 2025-09-23 eCollection Date: 2025-01-01 DOI:10.3389/fmed.2025.1620733

Na Jiang, Xiya Zheng, Nan Zhang, Yingjie Cao

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引用次数: 0

摘要

微塑料（MPs）是直径小于5毫米的塑料颗粒，主要来自塑料产品的降解（11）。近年来，议员对健康的影响也受到越来越多的关注。重要的问题已经浮出水面，包括MPs是否可以被肾脏清除，肾功能下降是否影响它们的清除，以及MP积累是否有助于肾脏疾病的进展。这篇综述探讨了MPs对肾脏的影响，并着重于它们的积累、毒性作用和潜在的分子机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

The detrimental effects of microplastic exposure on kidney function.

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The detrimental effects of microplastic exposure on kidney function.

Microplastics (MPs) are plastic particles with a diameter of less than 5 millimeters, primarily originating from the degradation of plastic products (11). In recent years, increasing attention has also been given to the impact of MPs on the health. Important questions have surfaced, including whether MPs can be cleared by the kidneys, whether reduced kidney function affects their clearance, and whether MP accumulation contributes to the progression of kidney diseases. This review explores the effects of MPs on the kidneys and focuses on their accumulation, toxic effects, and potential molecular mechanisms.

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来源期刊

Frontiers in Medicine Medicine-General Medicine

CiteScore

5.10

自引率

5.10%

发文量

3710

审稿时长

12 weeks

期刊介绍： Frontiers in Medicine publishes rigorously peer-reviewed research linking basic research to clinical practice and patient care, as well as translating scientific advances into new therapies and diagnostic tools. Led by an outstanding Editorial Board of international experts, this multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. In addition to papers that provide a link between basic research and clinical practice, a particular emphasis is given to studies that are directly relevant to patient care. In this spirit, the journal publishes the latest research results and medical knowledge that facilitate the translation of scientific advances into new therapies or diagnostic tools. The full listing of the Specialty Sections represented by Frontiers in Medicine is as listed below. As well as the established medical disciplines, Frontiers in Medicine is launching new sections that together will facilitate - the use of patient-reported outcomes under real world conditions - the exploitation of big data and the use of novel information and communication tools in the assessment of new medicines - the scientific bases for guidelines and decisions from regulatory authorities - access to medicinal products and medical devices worldwide - addressing the grand health challenges around the world