Qianqian Ni, Jing Wu, Christina Galanakou, Cheng-Cai Zhang, Donald A. Tomalia, Ling Peng
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Dendrimer engineering to overcome delivery challenges of nucleic acids
Dendrimers are precisely structured macromolecules with unique architectural symmetry and multivalency, offering a promising solution to the delivery challenges of nucleic acid therapeutics. Here, we explore recent advances in dendrimer design that enable targeted delivery to hard-to-transfect cells and difficult-to-reach tissues.
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