Lin Yang, Lianyong Han, Otmar Schmid, Chunying Chen
{"title":"肺给药的精确剂量学","authors":"Lin Yang, Lianyong Han, Otmar Schmid, Chunying Chen","doi":"10.1038/s44222-025-00356-9","DOIUrl":null,"url":null,"abstract":"Nanotechnology-based platforms are being explored for the delivery of therapeutics directly to the lungs through inhalation. However, to ensure translational relevance between preclinical animal models and human applications, it is essential to accurately quantify and report the lung-deposited dose, rather than relying solely on the nominally administered dose.","PeriodicalId":74248,"journal":{"name":"Nature reviews bioengineering","volume":"3 10","pages":"810-812"},"PeriodicalIF":37.6000,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Precision dosimetry in pulmonary drug delivery\",\"authors\":\"Lin Yang, Lianyong Han, Otmar Schmid, Chunying Chen\",\"doi\":\"10.1038/s44222-025-00356-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Nanotechnology-based platforms are being explored for the delivery of therapeutics directly to the lungs through inhalation. However, to ensure translational relevance between preclinical animal models and human applications, it is essential to accurately quantify and report the lung-deposited dose, rather than relying solely on the nominally administered dose.\",\"PeriodicalId\":74248,\"journal\":{\"name\":\"Nature reviews bioengineering\",\"volume\":\"3 10\",\"pages\":\"810-812\"},\"PeriodicalIF\":37.6000,\"publicationDate\":\"2025-08-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature reviews bioengineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.nature.com/articles/s44222-025-00356-9\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature reviews bioengineering","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s44222-025-00356-9","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Nanotechnology-based platforms are being explored for the delivery of therapeutics directly to the lungs through inhalation. However, to ensure translational relevance between preclinical animal models and human applications, it is essential to accurately quantify and report the lung-deposited dose, rather than relying solely on the nominally administered dose.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
