Anuradha C. Hugar, Manjunath S.Hanagadakar, Jagadish N. Hiremath, Anjanapura V. Raghu
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Antibacterial activity of Ag nanoparticles embedded tragacanth gum-based composite hydrogel synthesized with acrylamide and 2-acrylamido-2-methylpropanesulfonic acid
Ag nanoparticles (AgNPs) were successfully embedded into a tragacanth gum-based composite hydrogel, synthesized via free radical polymerization using acrylamide and 2-acrylamido-2-methylpropanesulfonic acid (AMPS). The resulting hydrogel exhibited enhanced thermal stability, as confirmed by thermogravimetric analysis, and a semi-crystalline structure observed in X-ray Diffraction analysis. Scanning electron microscope images revealed a uniform dispersion of AgNPs within the hydrogel matrix. Swelling studies revealed a maximum swelling ratio of 650% at pH 9.0 for the AgNPs-anchored hydrogel, significantly higher than the AgNP-free hydrogel. Elemental analysis indicated an Ag content of 7.2% by weight. Antibacterial assays demonstrated strong activity against both Escherichia coli and Staphylococcus aureus, with minimum inhibitory concentration values of 2500 µg/mL and 19.53 µg/mL, respectively. These results highlight the potential of the developed mTG-g-p(Am-co-AMPS)-Ag nanocomposite hydrogel as an effective antibacterial material for biomedical and environmental applications.
期刊介绍：
"Polymer Bulletin" is a comprehensive academic journal on polymer science founded in 1988. It was founded under the initiative of the late Mr. Wang Baoren, a famous Chinese chemist and educator. This journal is co-sponsored by the Chinese Chemical Society, the Institute of Chemistry, and the Chinese Academy of Sciences and is supervised by the China Association for Science and Technology. It is a core journal and is publicly distributed at home and abroad.
"Polymer Bulletin" is a monthly magazine with multiple columns, including a project application guide, outlook, review, research papers, highlight reviews, polymer education and teaching, information sharing, interviews, polymer science popularization, etc. The journal is included in the CSCD Chinese Science Citation Database. It serves as the source journal for Chinese scientific and technological paper statistics and the source journal of Peking University's "Overview of Chinese Core Journals."
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