儿童哮喘有什么新进展?

Q3 Medicine
Muhammad F Zulkifli, Michael P Yanney, Jayesh Mahendra Bhatt
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引用次数: 0

摘要

有充分的证据表明,英国儿童和年轻人的哮喘结果在欧洲和世界高收入国家中是最糟糕的。过去10年的几份报告对不良结果的原因进行了评估,报告结果之间高度一致。在这篇综述中,我们总结了这些报告的主要发现,以及全球哮喘倡议(GINA)和英国胸科学会(BTS)、国家健康与护理卓越研究所(NICE)和苏格兰校际指南网络(SIGN)哮喘指南最新更新的指南中如何采用新的治疗策略来解决这些问题。我们讨论早期和准确的哮喘诊断的重要性;对哮喘严重程度认识不足的问题以及短效β受体激动剂(SABA)过度使用和吸入皮质类固醇(ICS)使用不足的危险。我们总结了抗炎缓解(AIR)策略和维持和缓解治疗(MART)的证据,由于令人信服的证据显示它们对大多数治疗结果的积极影响,它们现在在所有新的哮喘指南中被提倡。最后,我们强调急性哮喘发作后出院儿童沙丁胺醇断奶指导的变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
What's new in paediatric asthma?
It is well documented that asthma outcomes for children and young people in the UK are amongst the worst in Europe and in high-income countries worldwide. Several reports in the last 10 years have evaluated the reasons for the poor outcomes, with a high degree of concordance between the report findings. In this review, we summarise the key findings of these reports and how they are being addressed by new treatment strategies in updated guidance published annually by the Global Initiative for Asthma (GINA) and the latest update of the joint British Thoracic Society (BTS), National Institute for Health and Care Excellence (NICE) and Scottish Intercollegiate Guidelines Network (SIGN) Asthma guideline. We discuss the importance of an early and accurate asthma diagnosis; the problem of poor recognition of asthma severity and the dangers of short acting beta agonists (SABA) overuse and inhaled corticosteroid (ICS) underuse. We summarise the evidence for anti-inflammatory reliever (AIR) strategy and maintenance and reliever therapy (MART) which are now advocated in all new asthma guidance due to compelling evidence showing their positive impact on most treatment outcome measures. Finally, we highlight changes to Salbutamol weaning guidance in children discharged from hospital following an acute asthma exacerbation.
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来源期刊
Paediatrics and Child Health (United Kingdom)
Paediatrics and Child Health (United Kingdom) Medicine-Pediatrics, Perinatology and Child Health
CiteScore
1.20
自引率
0.00%
发文量
70
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