对O’grady等人“区分胃轻瘫和功能性消化不良已经不够了”的回应

IF 25.8 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Gut Pub Date : 2025-10-08 DOI:10.1136/gutjnl-2025-336998

Michael Camilleri, Nicholas J Talley

{"title":"对O’grady等人“区分胃轻瘫和功能性消化不良已经不够了”的回应","authors":"Michael Camilleri, Nicholas J Talley","doi":"10.1136/gutjnl-2025-336998","DOIUrl":null,"url":null,"abstract":"We thank Drs O’Grady and colleagues for their interest1 in our commentary ‘Are functional dyspepsia and gastroparesis really ‘interchangeable’ diseases?’2 and their comment agreeing that improvement in tests of gastric emptying (GE) is highly desirable. Their plea for moving the field to understanding mechanisms and validating actionable biomarkers3 with the objective of personalising therapy4 is certainly consistent with our long track record. Consistent with the quest for pathophysiological characterisation of patients with symptoms considered to be arising in the stomach and duodenum, we previously published data on 1287 patients evaluated in the clinical practice using the …","PeriodicalId":12825,"journal":{"name":"Gut","volume":"32 1","pages":""},"PeriodicalIF":25.8000,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Response to: ‘Differentiating gastroparesis from functional dyspepsia is no longer sufficient’ by O’Grady et al\",\"authors\":\"Michael Camilleri, Nicholas J Talley\",\"doi\":\"10.1136/gutjnl-2025-336998\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We thank Drs O’Grady and colleagues for their interest1 in our commentary ‘Are functional dyspepsia and gastroparesis really ‘interchangeable’ diseases?’2 and their comment agreeing that improvement in tests of gastric emptying (GE) is highly desirable. Their plea for moving the field to understanding mechanisms and validating actionable biomarkers3 with the objective of personalising therapy4 is certainly consistent with our long track record. Consistent with the quest for pathophysiological characterisation of patients with symptoms considered to be arising in the stomach and duodenum, we previously published data on 1287 patients evaluated in the clinical practice using the …\",\"PeriodicalId\":12825,\"journal\":{\"name\":\"Gut\",\"volume\":\"32 1\",\"pages\":\"\"},\"PeriodicalIF\":25.8000,\"publicationDate\":\"2025-10-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gut\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1136/gutjnl-2025-336998\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gut","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1136/gutjnl-2025-336998","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

我们感谢O ' grady博士及其同事对我们的评论《功能性消化不良和胃轻瘫真的是可以“互换”的疾病吗？》他们的评论一致认为，改善胃排空（GE）测试是非常可取的。他们呼吁将这一领域推进到理解机制和验证可操作的生物标记物，以实现个性化治疗的目标，这与我们长期以来的记录是一致的。与对被认为是胃和十二指肠引起的症状的患者的病理生理特征的追求一致，我们先前发表了1287例患者的数据，在临床实践中使用…

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Response to: ‘Differentiating gastroparesis from functional dyspepsia is no longer sufficient’ by O’Grady et al

We thank Drs O’Grady and colleagues for their interest1 in our commentary ‘Are functional dyspepsia and gastroparesis really ‘interchangeable’ diseases?’2 and their comment agreeing that improvement in tests of gastric emptying (GE) is highly desirable. Their plea for moving the field to understanding mechanisms and validating actionable biomarkers3 with the objective of personalising therapy4 is certainly consistent with our long track record. Consistent with the quest for pathophysiological characterisation of patients with symptoms considered to be arising in the stomach and duodenum, we previously published data on 1287 patients evaluated in the clinical practice using the …

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Gut 医学-胃肠肝病学

CiteScore

45.70

自引率

2.40%

发文量

284

审稿时长

1.5 months

期刊介绍： Gut is a renowned international journal specializing in gastroenterology and hepatology, known for its high-quality clinical research covering the alimentary tract, liver, biliary tree, and pancreas. It offers authoritative and current coverage across all aspects of gastroenterology and hepatology, featuring articles on emerging disease mechanisms and innovative diagnostic and therapeutic approaches authored by leading experts. As the flagship journal of BMJ's gastroenterology portfolio, Gut is accompanied by two companion journals: Frontline Gastroenterology, focusing on education and practice-oriented papers, and BMJ Open Gastroenterology for open access original research.