高危肾细胞癌的辅助免疫治疗:适应症、局限性和前景。GIOTTO泌尿肿瘤小组的共识声明。

IF 5.6
Giandomenico Roviello, Federico Paolieri, Martina Catalano, Luca Galli, Laura Doni, Federico Peschiera, Alessandro Pili, Michele Sisani, Bloise Francesco
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引用次数: 0

摘要

肾细胞癌(RCC)通常在局部阶段诊断和手术治疗。然而,即使完全切除,仍有高达40%的患者可能出现复发。免疫检查点抑制剂,特别是派姆单抗的引入,已经改变了辅助治疗的前景。托斯卡纳跨学科泌尿肿瘤学小组(GIOTTO)为RCC患者选择和临床使用辅助派姆单抗提供实用指导。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Adjuvant Immunotherapy in High-Risk Renal Cell Carcinoma: Indications, Limitations, and Perspectives. A Consensus Statement from the GIOTTO Uro-Oncology Group.

Renal cell carcinoma (RCC) is often diagnosed at a localized stage and treated with surgery. However, up to 40% of patients may experience recurrence despite complete resection. The introduction of immune checkpoint inhibitors, particularly pembrolizumab, has changed the adjuvant treatment landscape. The Tuscan Interdisciplinary Uro-Oncological Group (GIOTTO) provides practical guidance on patient selection and clinical use of adjuvant pembrolizumab in RCC.

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