{"title":"抗微生物药物对马的不良影响。","authors":"Diego E Gomez, Jessica P Johnson","doi":"10.1016/j.cveq.2025.08.010","DOIUrl":null,"url":null,"abstract":"<p><p>Antimicrobial drug therapy in horses can lead to adverse effects across multiple body systems, with specific age groups, such as foals, at particular risk. Certain antimicrobial drugs, such as penicillins, aminoglycosides, macrolides, tetracyclines, and trimethoprim-sulfonamide combinations, are commonly implicated. This review explores the mechanisms behind these adverse reactions, emphasizing the importance of judicious antimicrobial drug use. This review also underscores the need for a centralized pharmacovigilance system to improve drug safety and adverse event reporting for veterinary medicine.</p>","PeriodicalId":49382,"journal":{"name":"Veterinary Clinics of North America-Equine Practice","volume":" ","pages":""},"PeriodicalIF":1.5000,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Adverse Effects of Antimicrobial Drugs Use in Horses.\",\"authors\":\"Diego E Gomez, Jessica P Johnson\",\"doi\":\"10.1016/j.cveq.2025.08.010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Antimicrobial drug therapy in horses can lead to adverse effects across multiple body systems, with specific age groups, such as foals, at particular risk. Certain antimicrobial drugs, such as penicillins, aminoglycosides, macrolides, tetracyclines, and trimethoprim-sulfonamide combinations, are commonly implicated. This review explores the mechanisms behind these adverse reactions, emphasizing the importance of judicious antimicrobial drug use. This review also underscores the need for a centralized pharmacovigilance system to improve drug safety and adverse event reporting for veterinary medicine.</p>\",\"PeriodicalId\":49382,\"journal\":{\"name\":\"Veterinary Clinics of North America-Equine Practice\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-10-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Veterinary Clinics of North America-Equine Practice\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.1016/j.cveq.2025.08.010\",\"RegionNum\":3,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Veterinary Clinics of North America-Equine Practice","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1016/j.cveq.2025.08.010","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Adverse Effects of Antimicrobial Drugs Use in Horses.
Antimicrobial drug therapy in horses can lead to adverse effects across multiple body systems, with specific age groups, such as foals, at particular risk. Certain antimicrobial drugs, such as penicillins, aminoglycosides, macrolides, tetracyclines, and trimethoprim-sulfonamide combinations, are commonly implicated. This review explores the mechanisms behind these adverse reactions, emphasizing the importance of judicious antimicrobial drug use. This review also underscores the need for a centralized pharmacovigilance system to improve drug safety and adverse event reporting for veterinary medicine.
期刊介绍:
Veterinary Clinics of North America: Equine Practice presents those in the veterinary medicine field with the most current treatment of horses, updates on the latest advances, and provides a sound basis for choosing treatment options. Published 3 times a year—in April, August, and December—each issue features expert, state-of-the-art reviews on a single topic in equine practice, including gastroenterology, imaging, infectious diseases, nutrition, orthopedics, pathology, pharmacology and therapeutics, and surgery.