优化儿科败血症诊断：从SIRS到凤凰共识的二十年演变的叙述性回顾。

IF 2.9 3区医学 Q2 INFECTIOUS DISEASES

Infection and Drug Resistance Pub Date : 2025-10-01 eCollection Date: 2025-01-01 DOI:10.2147/IDR.S544164

Banga Mseza, Walyeldin Elfakey

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引用次数: 0

摘要

从2005年国际儿童脓毒症共识会议（IPSCC）到2024年凤凰城脓毒症标准，儿科脓毒症的定义发生了重大变化。然而，先前模型的不一致性，包括全身性炎症反应综合征（SIRS）和败血症-3，影响了诊断和治疗。一个全球工作组进行了临床医生调查、荟萃分析和验证研究，最终将凤凰败血症评分作为一种完善的诊断模型。凤凰败血症评分评估四个器官系统，提高了诊断准确性，克服了早期模型的局限性。本文回顾了过去二十年来儿童败血症定义的演变，从2005年国际儿童败血症共识会议（IPSCC）标准到最近出版的凤凰败血症评分；提供标准化和全球相关的方法，以改善早期发现和治疗结果。

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Optimizing Pediatric Sepsis Diagnosis: A Narrative Review of Two Decades of Evolution from SIRS to Phoenix Consensus.

Pediatric sepsis definitions have evolved significantly from the 2005 International Pediatric Sepsis Consensus Conference (IPSCC) to the 2024 Phoenix Sepsis criteria. However, inconsistencies in previous models, including Systemic Inflammatory Response Syndrome (SIRS) and Sepsis-3, impacted diagnosis and treatment. A global task force conducted clinician surveys, meta-analysis, and validation studies, culminating in the Phoenix Sepsis Score as a refined diagnostic model. The Phoenix Sepsis Score assesses four organ systems, improving diagnostic accuracy and overcoming limitations seen in earlier models. This narrative review examines the evolution of pediatric sepsis definitions over the past two decades, from the 2005 International Pediatric Sepsis Consensus Conference (IPSCC) criteria to the recently published Phoenix Sepsis Score; providing a standardized and globally relevant approach to improving early detection and treatment outcomes.

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来源期刊

Infection and Drug Resistance Medicine-Pharmacology (medical)

CiteScore

5.60

自引率

7.70%

发文量

826

审稿时长

16 weeks

期刊介绍： About Journal Editors Peer Reviewers Articles Article Publishing Charges Aims and Scope Call For Papers ISSN: 1178-6973 Editor-in-Chief: Professor Suresh Antony An international, peer-reviewed, open access journal that focuses on the optimal treatment of infection (bacterial, fungal and viral) and the development and institution of preventative strategies to minimize the development and spread of resistance.