探索聚二氧杂环酮作为完全可吸收植入式传感器的衬底

IF 3.5
Finn Jaekel, Rakesh Nair, Laura Teuerle, Hans Kleemann, Kai Uhlig, Anna Katharina Sambale, Daniel C. Freund, Dennis Wahl, Eberhard Grambow, Sebastian Hinz, Clemens Schafmayer, Jochen Hampe, Karl Leo
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引用次数: 0

摘要

植入式和可吸收性电子设备在短期医疗监测方面表现出极好的潜力,特别是在手术后护理方面。生物可吸收传感器是特别感兴趣的,因为它们消除了手术回收的需要,从而减少了患者的风险和临床负担。在这项工作中,聚二氧环酮(PDO)是一种医学许可的、柔性的、可吸收的材料,作为生物可吸收电子元件集成的有前途的衬底。采用有针对性的、自下而上的方法,直接在PDO上演示了集成基本电子元件和传感器的可行性,包括电阻温度传感器、电解环境的电导率传感器、有机电化学晶体管和用于潜在无线通信的无源天线。这项工作突出了PDO作为未来完全可吸收医疗设备平台材料的潜力,并有助于不断增长的完全可吸收传感器技术工具包。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Exploring Polydioxanone as a Substrate for Fully Resorbable Implantable Sensors

Exploring Polydioxanone as a Substrate for Fully Resorbable Implantable Sensors

Implantable and resorbable electronic devices show excellent potential for short-term medical monitoring, especially in the context of post-surgical care. Bioresorbable sensors are of special interest, as they eliminate the need for surgical retrieval, thereby reducing patient risk and clinical burden. In this work, Polydioxanone (PDO) is explored, a medically licensed, flexible, resorbable material, as a promising substrate for the integration of bioresorbable electronic components. Using a targeted, bottom-up approach, the feasibility of integrating basic electronic elements and sensors is demonstrated directly on PDO, including resistive temperature sensors, conductivity sensors for electrolytic environments, organic electrochemical transistors, and passive antennas for potential wireless communication. This work highlights the potential of PDO as a platform material for future fully resorbable medical devices and contributes to the growing toolkit for fully resorbable sensor technologies.

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