超碱性阴离子钙烷基配合物：苯的二次去质子化模板

IF 16.9 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Angewandte Chemie International Edition Pub Date : 2025-10-08 DOI:10.1002/anie.202514283

Li Feng Lim, Ryan Huo, Flynn C. Attard, Morteza Jamshidi, Alireza Ariafard, Fabian Kallmeier, Jamie Hicks

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引用次数: 0

摘要

用阴离子氢化钙还原乙烯，合成了阴离子钙烷基配合物。烷基配合物被证明是超碱性的，在室温下迅速使醚脱质子，导致C─O键断裂。在与苯的反应中，观察到苯的选择性1,4 -金属化，形成反冠芳烃配合物。这种以前钙无法实现的转化通过逐步机制进行，也可以通过与有机金属试剂（如叔丁基锂和苯基钾）的共络合来促进。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Superbasic Anionic Calcium Alkyl Complexes: Templated Twofold Deprotonation of Benzene

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Superbasic Anionic Calcium Alkyl Complexes: Templated Twofold Deprotonation of Benzene

Anionic calcium alkyl complexes have been synthesised through the reduction of ethylene by an anionic calcium hydride. The alkyl complexes are demonstrated to be superbasic, rapidly deprotonating ethers below room temperature, leading to C─O bond cleavage. In reactions with benzene, selective 1,4‐metalation of benzene is observed, forming an inverse‐crown areneide complex. This transformation, previously inaccessible to calcium, proceeds via a stepwise mechanism, which can also be facilitated by co‐complexation with organometallic reagents such as tert‐butyllithium and phenylpotassium.

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来源期刊

Angewandte Chemie International Edition 化学-化学综合

CiteScore

26.60

自引率

6.60%

发文量

3549

审稿时长

1.5 months

期刊介绍： Angewandte Chemie, a journal of the German Chemical Society (GDCh), maintains a leading position among scholarly journals in general chemistry with an impressive Impact Factor of 16.6 (2022 Journal Citation Reports, Clarivate, 2023). Published weekly in a reader-friendly format, it features new articles almost every day. Established in 1887, Angewandte Chemie is a prominent chemistry journal, offering a dynamic blend of Review-type articles, Highlights, Communications, and Research Articles on a weekly basis, making it unique in the field.