{"title":"医护人员在工作时间内与不同类型的一次性外科口罩相关的泪膜和波前参数的变化：一项随机试验","authors":"Somporn Chantra, Nalinrat Disayavatin, Parinee Kemchoknatee","doi":"10.1177/25158414251378120","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Facial masks are essential for preventing respiratory infections, particularly among healthcare workers. However, prolonged mask use may lead to ocular surface disruption, known as mask-associated dry eye (MADE).</p><p><strong>Objectives: </strong>To evaluate the impact of different types of disposable surgical masks on tear film parameters and corneal wavefront aberrations during an 8-h work shift.</p><p><strong>Design: </strong>Randomized clinical trial.</p><p><strong>Methods: </strong>Sixty healthcare personnel at Rajavithi Hospital were randomly assigned to three mask groups: Group 1 (earloop surgical mask; Medimask<sup>®</sup>), Group 2 (earloop surgical mask with adhesive nose strip), and Group 3 (anti-fog earloop surgical mask; Welcare 3D Blue Line Anti-Fog Mask<sup>®</sup>). Non-invasive tear breakup time (NIBUT), tear meniscus height (TMH), and conjunctival redness were assessed using the Oculus Keratograph<sup>®</sup>5M. Corneal higher-order aberrations (HOAs) were measured using the GALILEI Dual Scheimpflug Analyzer before and after 8 h of mask wear.</p><p><strong>Results: </strong>TMH decreased significantly in all groups: Group 1 from 201.13 ± 85.10 µm to 174.53 ± 42.01 µm (<i>p</i> = 0.003), Group 2 from 188.81 ± 59.55 µm to 164.61 ± 50.58 µm (<i>p</i> = 0.036), and Group 3 from 194.50 ± 58.29 µm to 166.25 ± 45.90 µm (<i>p</i> = 0.034). NIBUT showed slight, non-significant decreases: Group 1 (9.26 ± 4.47-8.35 ± 3.26 s), Group 2 (8.88 ± 3.79-8.20 ± 3.12 s), and Group 3 (9.14 ± 4.20-8.55 ± 3.74 s). Conjunctival redness increased significantly only in Group 1 (1.75 ± 0.47-1.98 ± 0.52, <i>p</i> = 0.048). HOAs were mostly unchanged, except for total HOAs at the 6 mm zone, which were higher in Group 3 (1.85 ± 1.20) than in Group 1 (1.14 ± 0.48) and Group 2 (1.28 ± 0.58; <i>p</i> = 0.012).</p><p><strong>Conclusion: </strong>An 8-h shift of mask use reduced TMH across all groups and increased conjunctival redness in earloop surgical masks without adhesive. Although most optical aberrations remained unchanged, elevated HOAs in the anti-fog earloop surgical mask group may affect vision quality under mesopic conditions.</p><p><strong>Thai clinical trials registry: </strong>TCTR 20230725002 (https://www.thaiclinicaltrials.org/show/TCTR20230725002).</p>","PeriodicalId":23054,"journal":{"name":"Therapeutic Advances in Ophthalmology","volume":"17 ","pages":"25158414251378120"},"PeriodicalIF":2.3000,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496472/pdf/","citationCount":"0","resultStr":"{\"title\":\"Alterations in tear film and wavefront parameters associated with different types of disposable surgical masks in healthcare personnel during working hours: a randomized trial.\",\"authors\":\"Somporn Chantra, Nalinrat Disayavatin, Parinee Kemchoknatee\",\"doi\":\"10.1177/25158414251378120\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Facial masks are essential for preventing respiratory infections, particularly among healthcare workers. However, prolonged mask use may lead to ocular surface disruption, known as mask-associated dry eye (MADE).</p><p><strong>Objectives: </strong>To evaluate the impact of different types of disposable surgical masks on tear film parameters and corneal wavefront aberrations during an 8-h work shift.</p><p><strong>Design: </strong>Randomized clinical trial.</p><p><strong>Methods: </strong>Sixty healthcare personnel at Rajavithi Hospital were randomly assigned to three mask groups: Group 1 (earloop surgical mask; Medimask<sup>®</sup>), Group 2 (earloop surgical mask with adhesive nose strip), and Group 3 (anti-fog earloop surgical mask; Welcare 3D Blue Line Anti-Fog Mask<sup>®</sup>). Non-invasive tear breakup time (NIBUT), tear meniscus height (TMH), and conjunctival redness were assessed using the Oculus Keratograph<sup>®</sup>5M. Corneal higher-order aberrations (HOAs) were measured using the GALILEI Dual Scheimpflug Analyzer before and after 8 h of mask wear.</p><p><strong>Results: </strong>TMH decreased significantly in all groups: Group 1 from 201.13 ± 85.10 µm to 174.53 ± 42.01 µm (<i>p</i> = 0.003), Group 2 from 188.81 ± 59.55 µm to 164.61 ± 50.58 µm (<i>p</i> = 0.036), and Group 3 from 194.50 ± 58.29 µm to 166.25 ± 45.90 µm (<i>p</i> = 0.034). NIBUT showed slight, non-significant decreases: Group 1 (9.26 ± 4.47-8.35 ± 3.26 s), Group 2 (8.88 ± 3.79-8.20 ± 3.12 s), and Group 3 (9.14 ± 4.20-8.55 ± 3.74 s). Conjunctival redness increased significantly only in Group 1 (1.75 ± 0.47-1.98 ± 0.52, <i>p</i> = 0.048). HOAs were mostly unchanged, except for total HOAs at the 6 mm zone, which were higher in Group 3 (1.85 ± 1.20) than in Group 1 (1.14 ± 0.48) and Group 2 (1.28 ± 0.58; <i>p</i> = 0.012).</p><p><strong>Conclusion: </strong>An 8-h shift of mask use reduced TMH across all groups and increased conjunctival redness in earloop surgical masks without adhesive. Although most optical aberrations remained unchanged, elevated HOAs in the anti-fog earloop surgical mask group may affect vision quality under mesopic conditions.</p><p><strong>Thai clinical trials registry: </strong>TCTR 20230725002 (https://www.thaiclinicaltrials.org/show/TCTR20230725002).</p>\",\"PeriodicalId\":23054,\"journal\":{\"name\":\"Therapeutic Advances in Ophthalmology\",\"volume\":\"17 \",\"pages\":\"25158414251378120\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-10-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496472/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Therapeutic Advances in Ophthalmology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/25158414251378120\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Therapeutic Advances in Ophthalmology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/25158414251378120","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Alterations in tear film and wavefront parameters associated with different types of disposable surgical masks in healthcare personnel during working hours: a randomized trial.
Background: Facial masks are essential for preventing respiratory infections, particularly among healthcare workers. However, prolonged mask use may lead to ocular surface disruption, known as mask-associated dry eye (MADE).
Objectives: To evaluate the impact of different types of disposable surgical masks on tear film parameters and corneal wavefront aberrations during an 8-h work shift.
Design: Randomized clinical trial.
Methods: Sixty healthcare personnel at Rajavithi Hospital were randomly assigned to three mask groups: Group 1 (earloop surgical mask; Medimask®), Group 2 (earloop surgical mask with adhesive nose strip), and Group 3 (anti-fog earloop surgical mask; Welcare 3D Blue Line Anti-Fog Mask®). Non-invasive tear breakup time (NIBUT), tear meniscus height (TMH), and conjunctival redness were assessed using the Oculus Keratograph®5M. Corneal higher-order aberrations (HOAs) were measured using the GALILEI Dual Scheimpflug Analyzer before and after 8 h of mask wear.
Results: TMH decreased significantly in all groups: Group 1 from 201.13 ± 85.10 µm to 174.53 ± 42.01 µm (p = 0.003), Group 2 from 188.81 ± 59.55 µm to 164.61 ± 50.58 µm (p = 0.036), and Group 3 from 194.50 ± 58.29 µm to 166.25 ± 45.90 µm (p = 0.034). NIBUT showed slight, non-significant decreases: Group 1 (9.26 ± 4.47-8.35 ± 3.26 s), Group 2 (8.88 ± 3.79-8.20 ± 3.12 s), and Group 3 (9.14 ± 4.20-8.55 ± 3.74 s). Conjunctival redness increased significantly only in Group 1 (1.75 ± 0.47-1.98 ± 0.52, p = 0.048). HOAs were mostly unchanged, except for total HOAs at the 6 mm zone, which were higher in Group 3 (1.85 ± 1.20) than in Group 1 (1.14 ± 0.48) and Group 2 (1.28 ± 0.58; p = 0.012).
Conclusion: An 8-h shift of mask use reduced TMH across all groups and increased conjunctival redness in earloop surgical masks without adhesive. Although most optical aberrations remained unchanged, elevated HOAs in the anti-fog earloop surgical mask group may affect vision quality under mesopic conditions.
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