阿萨姆邦传统发酵竹芽的药物潜力:基于gc - ms的生物活性化合物分析。

IF 1.6 3区 化学 Q3 CHEMISTRY, APPLIED
Preety Priyam Saikia, Anil Bora
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引用次数: 0

摘要

本研究采用气相色谱-质谱联用技术(GC-MS)对印度阿萨姆邦传统发酵竹芽的生物活性成分和药用潜力进行了研究。幼芽收获后,按照当地做法发酵10-15天。GC-MS分析鉴定出28种挥发性生物活性化合物,包括酮类(47.35%)、酯类(26.08%)和倍半萜(10.04%),其中2-十一烷酮(36.85%)和十二烷酸乙烯酯(12.41%)为主要成分。对9个化合物进行了药理活性评价。值得注意的是,2-十一烷酮和神经树醇具有较强的抗菌和抗癌作用,而正十六烷酸具有较强的抗肿瘤和免疫增强作用。文献证据表明,与其他产自印度东北部的发酵竹笋相比,balcooa竹笋中的神经樟醇和十一烷酮含量较高,具有较强的抗癌和抗寄生虫作用。这项研究强调了发酵竹芽作为功能性食品的治疗潜力,植根于阿萨姆邦民族美食,提倡将其纳入制药和营养保健应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pharmaceutical potential of traditionally fermented Bambusa balcooa shoots from Assam: a GC-MS-based profiling of bioactive compounds.

This study explored the bioactive compounds and pharmaceutical potential of traditionally fermented Bambusa balcooa shoots from Assam, India, using gas chromatography-mass spectrometry (GC-MS). Young shoots were harvested and fermented for 10-15 days following indigenous practices. GC-MS analysis identified 28 volatile bioactive compounds, including ketones (47.35%), esters (26.08%), and sesquiterpenes (10.04%), with 2-undecanone (36.85%) and dodecanoic acid, ethenyl ester (12.41%) as dominant constituents. Nine compounds were evaluated for their pharmaceutical activities. Notably, 2-undecanone and nerolidol exhibited strong antimicrobial and anticancer effects, while n-hexadecanoic acid showed potent antitumour and immune-boosting properties. Compared with other fermented bamboo shoots from Northeast India, the higher levels of nerolidol and undecanone in B. balcooa indicate a stronger potential for anticancer and antiparasitic effects, based on literature evidence. This research underscores the therapeutic potential of fermented Bambusa balcooa shoots as functional foods rooted in Assam's ethnic cuisine, advocating their incorporation into pharmaceutical and nutraceutical applications.

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来源期刊
Natural Product Research
Natural Product Research 化学-医药化学
CiteScore
5.10
自引率
9.10%
发文量
605
审稿时长
2.1 months
期刊介绍: The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.
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