{"title":"CRP、PCT、TNF-a、d -乳酸、DAO、内毒素对重型颅脑损伤患者生存的预后价值","authors":"Ming Gong, Han Peng","doi":"10.5937/jomb0-54673","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Hyperbaric oxygen therapy is an important treatment method for early consciousness recovery and rehabilitation after brain trauma. In this study, we investigated the effects of hyperbaric oxygen combined with probiotics nutritional supplements (PNS) on patients with severe craniocerebral injury complicated with swallowing disorders in the Intensive care unit.</p><p><strong>Methods: </strong>Seventy-four patients with severe craniocerebral injury who received hyperbaric oxygen therapy in the ICU of our hospital from July 2020 to October 2023 were selected for retrospective analysis. Among them, 35 received conventional NS (control groups), and another 39 received PNS (research group). Inflammatory factors, T-lymphocyte subsets, and gastrointestinal mucosal function were compared between the two groups before and after treatment. In addition, patients' neurological function was assessed using the Glasgow Coma Scale (GCS), the Fugl-Meyer Assessment (FMA), and the National Institutes of Health Stroke Scale (NIHSS). Finally, the incidence of adverse effects between the two groups was counted.</p>","PeriodicalId":16175,"journal":{"name":"Journal of Medical Biochemistry","volume":"44 6","pages":"1340-1346"},"PeriodicalIF":1.5000,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12497459/pdf/","citationCount":"0","resultStr":"{\"title\":\"Prognostic value of CRP, PCT, and TNF-a, D-lactate, DAO, and endotoxin on survival of patients with severe craniocerebral injury.\",\"authors\":\"Ming Gong, Han Peng\",\"doi\":\"10.5937/jomb0-54673\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Hyperbaric oxygen therapy is an important treatment method for early consciousness recovery and rehabilitation after brain trauma. In this study, we investigated the effects of hyperbaric oxygen combined with probiotics nutritional supplements (PNS) on patients with severe craniocerebral injury complicated with swallowing disorders in the Intensive care unit.</p><p><strong>Methods: </strong>Seventy-four patients with severe craniocerebral injury who received hyperbaric oxygen therapy in the ICU of our hospital from July 2020 to October 2023 were selected for retrospective analysis. Among them, 35 received conventional NS (control groups), and another 39 received PNS (research group). Inflammatory factors, T-lymphocyte subsets, and gastrointestinal mucosal function were compared between the two groups before and after treatment. In addition, patients' neurological function was assessed using the Glasgow Coma Scale (GCS), the Fugl-Meyer Assessment (FMA), and the National Institutes of Health Stroke Scale (NIHSS). Finally, the incidence of adverse effects between the two groups was counted.</p>\",\"PeriodicalId\":16175,\"journal\":{\"name\":\"Journal of Medical Biochemistry\",\"volume\":\"44 6\",\"pages\":\"1340-1346\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-09-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12497459/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Medical Biochemistry\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.5937/jomb0-54673\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Biochemistry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5937/jomb0-54673","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
Prognostic value of CRP, PCT, and TNF-a, D-lactate, DAO, and endotoxin on survival of patients with severe craniocerebral injury.
Background: Hyperbaric oxygen therapy is an important treatment method for early consciousness recovery and rehabilitation after brain trauma. In this study, we investigated the effects of hyperbaric oxygen combined with probiotics nutritional supplements (PNS) on patients with severe craniocerebral injury complicated with swallowing disorders in the Intensive care unit.
Methods: Seventy-four patients with severe craniocerebral injury who received hyperbaric oxygen therapy in the ICU of our hospital from July 2020 to October 2023 were selected for retrospective analysis. Among them, 35 received conventional NS (control groups), and another 39 received PNS (research group). Inflammatory factors, T-lymphocyte subsets, and gastrointestinal mucosal function were compared between the two groups before and after treatment. In addition, patients' neurological function was assessed using the Glasgow Coma Scale (GCS), the Fugl-Meyer Assessment (FMA), and the National Institutes of Health Stroke Scale (NIHSS). Finally, the incidence of adverse effects between the two groups was counted.
期刊介绍：
The JOURNAL OF MEDICAL BIOCHEMISTRY (J MED BIOCHEM) is the official journal of the Society of Medical Biochemists of Serbia with international peer-review. Papers are independently reviewed by at least two reviewers selected by the Editors as Blind Peer Reviews. The Journal of Medical Biochemistry is published quarterly.
The Journal publishes original scientific and specialized articles on all aspects of
clinical and medical biochemistry,
molecular medicine,
clinical hematology and coagulation,
clinical immunology and autoimmunity,
clinical microbiology,
virology,
clinical genomics and molecular biology,
genetic epidemiology,
drug measurement,
evaluation of diagnostic markers,
new reagents and laboratory equipment,
reference materials and methods,
reference values,
laboratory organization,
automation,
quality control,
clinical metrology,
all related scientific disciplines where chemistry, biochemistry, molecular biology and immunochemistry deal with the study of normal and pathologic processes in human beings.
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