Diagnostic levels of C-reactive protein (CRP), epinephrine (EP), cortisol (COR), and norepinephrine (NE) in patients undergoing laparoscopic surgery for gallstones receiving anti-inflammatory therapy.

Background: The study aimed to investigate the effect of anti-inflammatory and choleretic soup on CRP, Ep, Cor, NE, and gallbladder function recovery in patients following laparoscopic cholecystectomy.

Methods: A total of 111 patients with gallstones who underwent laparoscopic surgery at the hospital between November 2019 and March 2024 were selected. All patients were randomly assigned to two groups using a random number method. The control group (n=56) received extracorporeal circulation treatment alone, while the experimental group (n=55) received additional treatment with anti-inflammatory bile soup. Differences in the levels of C-reactive protein (CRP), epinephrine (Ep), cortisol (Cor), and norepinephrine (NE) were compared and analysed between the two groups. The effects on gallbladder function recovery were also evaluated.

Results: Three months post-treatment, the levels of CRP, Ep, Cor, and NE in both groups had decreased compared to pre-treatment levels. Post-treatment levels of these indices were significantly lower in the experimental group than in the control group (P<0.05). Furthermore, the gallbladder wall thickness and fasting gallbladder volume (FV) in both groups were reduced compared to pre-treatment levels, while the gallbladder contraction rate improved. The experimental group exhibited better gallbladder function outcomes across various indices than the control group (P<0.05).

Conclusions: The application of anti-inflammatory and choleretic soup in patients following laparoscopic cholecystectomy contributes to improvements in physiological parameters, enhances the recovery of gallbladder functional indices, and improves the quality of life during prognosis and rehabilitation.