Bartłomiej Błaszczyk, Helena Martynowicz, Mieszko Więckiewicz, Sławomir Budrewicz, Marta Waliszewska-Prosół
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All results were adjusted for medication use in the treatment of migraine, which may interfere with sleep and SB.</p><p><strong>Results: </strong>A total of 110 patients with migraine (mean age: 39.3 years; 88% female) were evaluated, including 65 individuals with CM and 45 episodic migraine (EM) patients. The patients with CM had lower REM sleep duration when compared to those with EM (median (Me): 21.4% of total sleep time (TST) vs. 24.4% of TST, p = 0.008), while REM sleep below 23.1% of TST was associated with increased odds of CM (odds ratio (OR): 3.61 (95% confidence interval (CI): 1.60; 8.15), p = 0.002). Seventy-six out of 110 (69%) participants were diagnosed with SB. The presence of mixed bruxism at a frequency of above 0.4 episodes per hour (n/h) was associated with increased odds of CM (OR: 2.40 (95% CI: 1.06; 5.46), p = 0.048). However, severe SB (bruxism episode index (BEI) >4) was associated with increased odds of migraine with aura (MwA) (OR: 2.68 (95% CI: 1.05; 6.83), p = 0.044). Migraine without aura showed a weak, negative correlation with BEI (r = -0.293, p = 0.002).</p><p><strong>Conclusions: </strong>A decrease in the REM stage of sleep was associated with CM. Despite the high prevalence of SB in patients with migraine, SB was not associated with CM, while severe bruxism was associated with MwA. Therefore, if any association between SB and migraine exists, it is more likely related to aura phenomena than to migraine chronification.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":" ","pages":""},"PeriodicalIF":3.9000,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sleep bruxism and sleep architecture in chronic migraine: A polysomnographic study.\",\"authors\":\"Bartłomiej Błaszczyk, Helena Martynowicz, Mieszko Więckiewicz, Sławomir Budrewicz, Marta Waliszewska-Prosół\",\"doi\":\"10.17219/dmp/210439\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Despite the fact that sleep bruxism (SB) is common in migraine, and that patients with migraine often report poor sleep quality, SB and sleep architecture in chronic migraine (CM) have not been fully explored.</p><p><strong>Objectives: </strong>The aim of the study was to establish the association between SB and CM, with an assessment of sleep structure alterations in CM.</p><p><strong>Material and methods: </strong>The diagnosis of migraine was made using the 3rd edition of the International Classification of Headache Disorders (ICHD-3). Sleep bruxism and sleep structure were assessed using polysomnography, according to the American Academy of Sleep Medicine (AASM) Guidelines. All results were adjusted for medication use in the treatment of migraine, which may interfere with sleep and SB.</p><p><strong>Results: </strong>A total of 110 patients with migraine (mean age: 39.3 years; 88% female) were evaluated, including 65 individuals with CM and 45 episodic migraine (EM) patients. The patients with CM had lower REM sleep duration when compared to those with EM (median (Me): 21.4% of total sleep time (TST) vs. 24.4% of TST, p = 0.008), while REM sleep below 23.1% of TST was associated with increased odds of CM (odds ratio (OR): 3.61 (95% confidence interval (CI): 1.60; 8.15), p = 0.002). Seventy-six out of 110 (69%) participants were diagnosed with SB. The presence of mixed bruxism at a frequency of above 0.4 episodes per hour (n/h) was associated with increased odds of CM (OR: 2.40 (95% CI: 1.06; 5.46), p = 0.048). However, severe SB (bruxism episode index (BEI) >4) was associated with increased odds of migraine with aura (MwA) (OR: 2.68 (95% CI: 1.05; 6.83), p = 0.044). Migraine without aura showed a weak, negative correlation with BEI (r = -0.293, p = 0.002).</p><p><strong>Conclusions: </strong>A decrease in the REM stage of sleep was associated with CM. Despite the high prevalence of SB in patients with migraine, SB was not associated with CM, while severe bruxism was associated with MwA. 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引用次数: 0
摘要
背景：尽管睡眠磨牙症（SB）在偏头痛中很常见，并且偏头痛患者经常报告睡眠质量差，但慢性偏头痛（CM）的SB和睡眠结构尚未得到充分探讨。目的：本研究的目的是建立SB和CM之间的联系，并评估CM的睡眠结构改变。材料和方法：偏头痛的诊断采用第3版国际头痛疾病分类（ICHD-3）。根据美国睡眠医学学会（AASM）指南，睡眠磨牙症和睡眠结构使用多导睡眠图进行评估。结果：共评估了110例偏头痛患者（平均年龄：39.3岁，88%为女性），包括65例CM患者和45例发作性偏头痛（EM）患者。与EM患者相比，CM患者的REM睡眠时间较短（中位数（Me）：占总睡眠时间（TST）的21.4% vs.占总睡眠时间的24.4%,p = 0.008），而REM睡眠低于总睡眠时间的23.1%与CM的几率增加相关(优势比（OR）： 3.61(95%可信区间（CI）： 1.60；8.15), p = 0.002)。110名参与者中有76人（69%）被诊断为SB。每小时（n/h）出现频率超过0.4次的混合性磨牙与CM的几率增加相关（OR: 2.40 (95% CI: 1.06; 5.46), p = 0.048）。然而，严重的SB（磨牙发作指数（BEI） bbbb4）与先兆偏头痛（MwA）的发生率增加相关（OR: 2.68 (95% CI: 1.05; 6.83), p = 0.044）。无先兆偏头痛与BEI呈弱负相关（r = -0.293, p = 0.002）。结论：快速眼动期睡眠减少与CM有关。尽管SB在偏头痛患者中发病率很高，但SB与CM无关，而严重的磨牙症与MwA相关。因此，如果SB和偏头痛之间存在任何关联，它更可能与先兆现象有关，而不是偏头痛的慢性化。
Sleep bruxism and sleep architecture in chronic migraine: A polysomnographic study.
Background: Despite the fact that sleep bruxism (SB) is common in migraine, and that patients with migraine often report poor sleep quality, SB and sleep architecture in chronic migraine (CM) have not been fully explored.
Objectives: The aim of the study was to establish the association between SB and CM, with an assessment of sleep structure alterations in CM.
Material and methods: The diagnosis of migraine was made using the 3rd edition of the International Classification of Headache Disorders (ICHD-3). Sleep bruxism and sleep structure were assessed using polysomnography, according to the American Academy of Sleep Medicine (AASM) Guidelines. All results were adjusted for medication use in the treatment of migraine, which may interfere with sleep and SB.
Results: A total of 110 patients with migraine (mean age: 39.3 years; 88% female) were evaluated, including 65 individuals with CM and 45 episodic migraine (EM) patients. The patients with CM had lower REM sleep duration when compared to those with EM (median (Me): 21.4% of total sleep time (TST) vs. 24.4% of TST, p = 0.008), while REM sleep below 23.1% of TST was associated with increased odds of CM (odds ratio (OR): 3.61 (95% confidence interval (CI): 1.60; 8.15), p = 0.002). Seventy-six out of 110 (69%) participants were diagnosed with SB. The presence of mixed bruxism at a frequency of above 0.4 episodes per hour (n/h) was associated with increased odds of CM (OR: 2.40 (95% CI: 1.06; 5.46), p = 0.048). However, severe SB (bruxism episode index (BEI) >4) was associated with increased odds of migraine with aura (MwA) (OR: 2.68 (95% CI: 1.05; 6.83), p = 0.044). Migraine without aura showed a weak, negative correlation with BEI (r = -0.293, p = 0.002).
Conclusions: A decrease in the REM stage of sleep was associated with CM. Despite the high prevalence of SB in patients with migraine, SB was not associated with CM, while severe bruxism was associated with MwA. Therefore, if any association between SB and migraine exists, it is more likely related to aura phenomena than to migraine chronification.
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