新型喹啉基荧光探针对亚硫酸盐的灵敏检测及其在食品检测和生物成像中的应用。

IF 2.6 3区化学 Q2 CHEMISTRY, ANALYTICAL

Analytical Methods Pub Date : 2025-10-16 DOI:10.1039/d5ay01291k

Lewei Gao, Mengdi Zhao, Yue Gu, Shuai Gong, Yueyin Liang, Zhiyuan Meng, Yixin Yang, Zhonglong Wang, Shifa Wang

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引用次数: 0

摘要

亚硫酸氢盐（HSO3-）是一种广泛使用的食品添加剂，在许多生理过程中起着至关重要的作用。然而，过量的HSO3-会对人体健康造成不可预测的风险。因此，监测食品样品中的HSO3-残留量对保障人类健康至关重要。本文以樟脑醌为原料合成了一种用于检测HSO3-的比例荧光探针（DPTI）。该探针在10 min内对HSO3-具有高选择性（LOD = 0.07 μM）的比色和荧光双响应。此外，DPTI探针可用于食品样品中HSO3-含量的检测。此外，DPTI探针良好的生物相容性使其适合于活体中HSO3-的荧光生物成像。

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Sensitive detection of bisulfite by a novel quinoxalinyl-based fluorescent probe and its applications in food detection and bioimaging.

Bisulfite (HSO₃^-) is a widely used food additive that plays a crucial role in many physiological processes. Nevertheless, excessive amounts of HSO₃^- can pose unpredictable risks to human health. Hence, monitoring residual HSO₃^- in food samples is crucial for safeguarding human health. In this work, a ratiometric fluorescent probe (DPTI) for detecting HSO₃^- was synthesized, derived from camphorquinone. This probe showed a colorimetric and fluorescence dual response to HSO₃^- within 10 min with high selectivity (LOD = 0.07 μM). In addition, the DPTI probe could be used for detecting HSO₃^- content in food samples. Additionally, the good biocompatibility of the DPTI probe makes it suitable for the fluorescence bioimaging of HSO₃^- in living organisms.