以狼烷和熊烷系三萜为原料合成C28硝基酮

IF 0.8 4区化学 Q4 CHEMISTRY, MULTIDISCIPLINARY

Russian Journal of General Chemistry Pub Date : 2025-10-07 DOI:10.1134/S1070363225604053

N. G. Komissarova, A. V. Orlov, L. V. Spirikhin

{"title":"以狼烷和熊烷系三萜为原料合成C28硝基酮","authors":"N. G. Komissarova, A. V. Orlov, L. V. Spirikhin","doi":"10.1134/S1070363225604053","DOIUrl":null,"url":null,"abstract":"New nitrone-containing derivatives of pentacyclic triterpenoids were synthesized based on ursolic and betulonic acids. Their nitrone function is attached to the triterpenoid core at the C28 position via a benzylamide spacer. The resulting nitrones are of interest as potentially biologically active compounds a wide range of pharmacological effects.","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"95 9","pages":"2350 - 2357"},"PeriodicalIF":0.8000,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1134/S1070363225604053.pdf","citationCount":"0","resultStr":"{\"title\":\"Synthesis of C28 Nitrones Based on Triterpenoids of the Lupane and Ursane Series\",\"authors\":\"N. G. Komissarova, A. V. Orlov, L. V. Spirikhin\",\"doi\":\"10.1134/S1070363225604053\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"New nitrone-containing derivatives of pentacyclic triterpenoids were synthesized based on ursolic and betulonic acids. Their nitrone function is attached to the triterpenoid core at the C28 position via a benzylamide spacer. The resulting nitrones are of interest as potentially biologically active compounds a wide range of pharmacological effects.\",\"PeriodicalId\":761,\"journal\":{\"name\":\"Russian Journal of General Chemistry\",\"volume\":\"95 9\",\"pages\":\"2350 - 2357\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2025-10-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://link.springer.com/content/pdf/10.1134/S1070363225604053.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Journal of General Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S1070363225604053\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of General Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S1070363225604053","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

摘要

以熊果酸和桦木烯酸为原料合成了新的含硝基的五环三萜衍生物。它们的硝基酮功能通过苄酰胺间隔剂连接到C28位置的三萜核心上。由此产生的硝基化合物具有广泛的药理作用，具有潜在的生物活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Synthesis of C28 Nitrones Based on Triterpenoids of the Lupane and Ursane Series

New nitrone-containing derivatives of pentacyclic triterpenoids were synthesized based on ursolic and betulonic acids. Their nitrone function is attached to the triterpenoid core at the C²⁸ position via a benzylamide spacer. The resulting nitrones are of interest as potentially biologically active compounds a wide range of pharmacological effects.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Russian Journal of General Chemistry 化学-化学综合

CiteScore

1.40

自引率

22.20%

发文量

252

审稿时长

2-4 weeks

期刊介绍： Russian Journal of General Chemistry is a journal that covers many problems that are of general interest to the whole community of chemists. The journal is the successor to Russia’s first chemical journal, Zhurnal Russkogo Khimicheskogo Obshchestva (Journal of the Russian Chemical Society ) founded in 1869 to cover all aspects of chemistry. Now the journal is focused on the interdisciplinary areas of chemistry (organometallics, organometalloids, organoinorganic complexes, mechanochemistry, nanochemistry, etc.), new achievements and long-term results in the field. The journal publishes reviews, current scientific papers, letters to the editor, and discussion papers.