光学相干断层扫描对健康人群与圆锥角膜患者巩膜形态的比较。

IF 2.6
Chao Wan, Longwang Wu, Zhixiang Yan, Bo Liu, Tao Yu, Ke Wang, Xiangyu He, Yuli Yang
{"title":"光学相干断层扫描对健康人群与圆锥角膜患者巩膜形态的比较。","authors":"Chao Wan, Longwang Wu, Zhixiang Yan, Bo Liu, Tao Yu, Ke Wang, Xiangyu He, Yuli Yang","doi":"10.1016/j.pdpdt.2025.105243","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To scan and measure the scleral morphology of healthy eyes and keratoconus eyes using Optical Coherence Tomography (OCT), evaluate the differences in scleral morphology between them, and provide a more scientific basis for the precise fitting of scleral lenses.</p><p><strong>Methods: </strong>A total of 85 subjects who were admitted to the First Affiliated Hospital of Army Medical University from March 2024 to November 2024 and underwent OCT examination were selected as the research subjects. They were divided into a healthy group (64 cases, 120 eyes) and a keratoconus group (21 cases, 40 eyes) according to whether they had the disease. Each subject underwent anterior segment OCT examination to measure and obtain corneoscleral parameters such as the Corneoscleral Junction Angle (CSJA), Scleral Angle (SA), Sagittal Height (SH), and Scleral Toricity (ST). The differences in the above parameters at different chord lengths and in different orientations were compared, and these parameters of the two groups of subjects were also compared.</p><p><strong>Results: </strong>In both groups, the CSJA was the largest in the superior position and the smallest in the nasal position, and the difference was statistically significant (P<0.05). The average nasal CSJA in the keratoconus group was 175.6°, while that in the healthy group was 177.0°, and the difference was statistically significant (P<0.05). In the healthy group, at a chord length of 10.0 mm, the SA was the largest in the superonasal position and the smallest in the temporal position; at chord lengths of 12.8 mm, 14.0 mm, and 15.0 mm, the SA was the largest in the temporal position and the smallest in the superonasal position, and the difference was statistically significant (P<0.05). In the keratoconus group, at a chord length of 10.0 mm, the SA was the largest in the superonasal position and the smallest in the temporal position; at a chord length of 12.8 mm, the SA was the largest in the temporal position and the smallest in the superonasal position; at chord lengths of 14.0 mm and 15.0 mm, the SA was the largest in the inferotemporal position and the smallest in the nasal position, and the difference was statistically significant (P<0.05). At chord lengths of 10.0 mm, 12.8 mm, 14.0 mm, and 15.0 mm, the SH in the keratoconus group was greater than that in the healthy group, and the difference was statistically significant (P<0.05). The ST of both groups increased with the increase of the chord length. In the healthy group, the ST increased from 0.06 mm at chord length of 10.0 mm to 0.16 mm at chord length of 15.0 mm. In the keratoconus group, the ST increased from 0.11 mm at chord length of 10.0 mm to 0.20 mm at chord length of 15.0 mm, and the difference was statistically significant (P<0.05); at chord lengths of 10.0 mm, 12.8 mm, 14.0 mm, and 15.0 mm, the ST in the keratoconus group was greater than that in the healthy group, and the difference was statistically significant (P<0.05).</p><p><strong>Conclusion: </strong>The sclera is generally irregular in shape, especially extremely asymmetric in the horizontal direction. Moreover, as the chord length increases, this irregularity becomes more obvious. Compared with healthy eyes, the scleral morphology of keratoconus eyes shows more significant irregularities.</p>","PeriodicalId":94170,"journal":{"name":"Photodiagnosis and photodynamic therapy","volume":" ","pages":"105243"},"PeriodicalIF":2.6000,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Compare of the scleral morphology between healthy populations and keratoconus patients using optical coherence tomography.\",\"authors\":\"Chao Wan, Longwang Wu, Zhixiang Yan, Bo Liu, Tao Yu, Ke Wang, Xiangyu He, Yuli Yang\",\"doi\":\"10.1016/j.pdpdt.2025.105243\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To scan and measure the scleral morphology of healthy eyes and keratoconus eyes using Optical Coherence Tomography (OCT), evaluate the differences in scleral morphology between them, and provide a more scientific basis for the precise fitting of scleral lenses.</p><p><strong>Methods: </strong>A total of 85 subjects who were admitted to the First Affiliated Hospital of Army Medical University from March 2024 to November 2024 and underwent OCT examination were selected as the research subjects. They were divided into a healthy group (64 cases, 120 eyes) and a keratoconus group (21 cases, 40 eyes) according to whether they had the disease. Each subject underwent anterior segment OCT examination to measure and obtain corneoscleral parameters such as the Corneoscleral Junction Angle (CSJA), Scleral Angle (SA), Sagittal Height (SH), and Scleral Toricity (ST). The differences in the above parameters at different chord lengths and in different orientations were compared, and these parameters of the two groups of subjects were also compared.</p><p><strong>Results: </strong>In both groups, the CSJA was the largest in the superior position and the smallest in the nasal position, and the difference was statistically significant (P<0.05). The average nasal CSJA in the keratoconus group was 175.6°, while that in the healthy group was 177.0°, and the difference was statistically significant (P<0.05). In the healthy group, at a chord length of 10.0 mm, the SA was the largest in the superonasal position and the smallest in the temporal position; at chord lengths of 12.8 mm, 14.0 mm, and 15.0 mm, the SA was the largest in the temporal position and the smallest in the superonasal position, and the difference was statistically significant (P<0.05). In the keratoconus group, at a chord length of 10.0 mm, the SA was the largest in the superonasal position and the smallest in the temporal position; at a chord length of 12.8 mm, the SA was the largest in the temporal position and the smallest in the superonasal position; at chord lengths of 14.0 mm and 15.0 mm, the SA was the largest in the inferotemporal position and the smallest in the nasal position, and the difference was statistically significant (P<0.05). At chord lengths of 10.0 mm, 12.8 mm, 14.0 mm, and 15.0 mm, the SH in the keratoconus group was greater than that in the healthy group, and the difference was statistically significant (P<0.05). The ST of both groups increased with the increase of the chord length. In the healthy group, the ST increased from 0.06 mm at chord length of 10.0 mm to 0.16 mm at chord length of 15.0 mm. In the keratoconus group, the ST increased from 0.11 mm at chord length of 10.0 mm to 0.20 mm at chord length of 15.0 mm, and the difference was statistically significant (P<0.05); at chord lengths of 10.0 mm, 12.8 mm, 14.0 mm, and 15.0 mm, the ST in the keratoconus group was greater than that in the healthy group, and the difference was statistically significant (P<0.05).</p><p><strong>Conclusion: </strong>The sclera is generally irregular in shape, especially extremely asymmetric in the horizontal direction. Moreover, as the chord length increases, this irregularity becomes more obvious. Compared with healthy eyes, the scleral morphology of keratoconus eyes shows more significant irregularities.</p>\",\"PeriodicalId\":94170,\"journal\":{\"name\":\"Photodiagnosis and photodynamic therapy\",\"volume\":\" \",\"pages\":\"105243\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2025-10-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Photodiagnosis and photodynamic therapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.pdpdt.2025.105243\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Photodiagnosis and photodynamic therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.pdpdt.2025.105243","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

目的:利用光学相干断层扫描(OCT)对健康眼和圆锥角膜眼的巩膜形态进行扫描测量,评价二者巩膜形态的差异,为巩膜晶状体的精确配合术提供更科学的依据。方法:选取2024年3月至2024年11月陆军军医大学第一附属医院住院并行OCT检查的85名受试者作为研究对象。根据是否患病分为健康组(64例,120只眼)和圆锥角膜组(21例,40只眼)。每位受试者接受前段OCT检查,测量并获得角膜巩膜参数,如角膜巩膜连接角(CSJA)、巩膜角(SA)、矢状高度(SH)和巩膜圆环度(ST)。比较上述参数在不同弦长和不同方向上的差异,并比较两组被试的这些参数。结果:两组巩膜上位最大,鼻位最小,差异均有统计学意义(p结论:巩膜形状普遍不规则,尤其是水平方向极为不对称。而且,随着弦长的增加,这种不规则性变得更加明显。圆锥角膜眼的巩膜形态与正常眼相比有明显的不规则性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Compare of the scleral morphology between healthy populations and keratoconus patients using optical coherence tomography.

Objective: To scan and measure the scleral morphology of healthy eyes and keratoconus eyes using Optical Coherence Tomography (OCT), evaluate the differences in scleral morphology between them, and provide a more scientific basis for the precise fitting of scleral lenses.

Methods: A total of 85 subjects who were admitted to the First Affiliated Hospital of Army Medical University from March 2024 to November 2024 and underwent OCT examination were selected as the research subjects. They were divided into a healthy group (64 cases, 120 eyes) and a keratoconus group (21 cases, 40 eyes) according to whether they had the disease. Each subject underwent anterior segment OCT examination to measure and obtain corneoscleral parameters such as the Corneoscleral Junction Angle (CSJA), Scleral Angle (SA), Sagittal Height (SH), and Scleral Toricity (ST). The differences in the above parameters at different chord lengths and in different orientations were compared, and these parameters of the two groups of subjects were also compared.

Results: In both groups, the CSJA was the largest in the superior position and the smallest in the nasal position, and the difference was statistically significant (P<0.05). The average nasal CSJA in the keratoconus group was 175.6°, while that in the healthy group was 177.0°, and the difference was statistically significant (P<0.05). In the healthy group, at a chord length of 10.0 mm, the SA was the largest in the superonasal position and the smallest in the temporal position; at chord lengths of 12.8 mm, 14.0 mm, and 15.0 mm, the SA was the largest in the temporal position and the smallest in the superonasal position, and the difference was statistically significant (P<0.05). In the keratoconus group, at a chord length of 10.0 mm, the SA was the largest in the superonasal position and the smallest in the temporal position; at a chord length of 12.8 mm, the SA was the largest in the temporal position and the smallest in the superonasal position; at chord lengths of 14.0 mm and 15.0 mm, the SA was the largest in the inferotemporal position and the smallest in the nasal position, and the difference was statistically significant (P<0.05). At chord lengths of 10.0 mm, 12.8 mm, 14.0 mm, and 15.0 mm, the SH in the keratoconus group was greater than that in the healthy group, and the difference was statistically significant (P<0.05). The ST of both groups increased with the increase of the chord length. In the healthy group, the ST increased from 0.06 mm at chord length of 10.0 mm to 0.16 mm at chord length of 15.0 mm. In the keratoconus group, the ST increased from 0.11 mm at chord length of 10.0 mm to 0.20 mm at chord length of 15.0 mm, and the difference was statistically significant (P<0.05); at chord lengths of 10.0 mm, 12.8 mm, 14.0 mm, and 15.0 mm, the ST in the keratoconus group was greater than that in the healthy group, and the difference was statistically significant (P<0.05).

Conclusion: The sclera is generally irregular in shape, especially extremely asymmetric in the horizontal direction. Moreover, as the chord length increases, this irregularity becomes more obvious. Compared with healthy eyes, the scleral morphology of keratoconus eyes shows more significant irregularities.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信