Mohammed M Alnawmasi, Nawaf M Almutairi, Sieu K Khuu
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Patients with mTBI had reduced pupil dilation when tracking a high number of target dots (four dots: Mean difference [MD] = 0.79, p < 0.001; five dots: MD = 0.67, p < 0.001) compared to controls. Similarly, patients with mTBI had reduced pupil dilation when the number of distractor dots increased (six distractors: MD = 0.43, p < 0.001; nine distractors: MD = 0.46, p < 0.001) compared to controls. A reduction in pupil dilation observed in patients with mTBI may reflect a limitation in the mental capacity to meet increasing cognitive demands. Eye movement analysis showed that patients with mTBI made significantly more fixations (and with reduced fixation durations), consistent with a local tracking strategy, than controls. 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引用次数: 0
摘要
据报道,轻度创伤性脑损伤(mTBI)患者维持视觉注意力追踪多个运动物体的能力受损。我们研究了mTBI后多目标追踪(MOT)缺陷是否与注意的行为标记有关,特别是认知驱动的瞳孔扩张反应和眼动模式。招募了35名成年人。当参与者执行一项MOT任务时,瞳孔反应和眼球运动被跟踪,其中跟踪的持续时间(5秒和10秒)、目标点的数量(3、4和5)和分心点的数量(3、6和9)是独立变量。与对照组相比,mTBI患者在跟踪大量目标点(4个点:平均差值[MD] = 0.79, p < 0.001; 5个点:MD = 0.67, p < 0.001)时瞳孔扩张减小。同样,与对照组相比,mTBI患者瞳孔扩张随着牵张器点数的增加而减小(6个牵张器:MD = 0.43, p < 0.001; 9个牵张器:MD = 0.46, p < 0.001)。在mTBI患者中观察到瞳孔扩张的减少可能反映了心智能力的限制,以满足不断增加的认知需求。眼动分析显示,与对照组相比,mTBI患者的注视次数明显增加(注视时间缩短),与局部跟踪策略一致。总之,在跟踪多个运动物体的同时跟踪瞳孔反应和眼球运动,为mTBI患者表现不佳的可能因素提供了指示。
A pupillary and eye movement investigation of functional deficits in multiple object tracking following mild traumatic brain injury.
The ability to maintain visual attention to track multiple moving objects has been reported to be impaired in individuals with mild traumatic brain injury (mTBI). We investigated whether deficits in multiple object tracking (MOT) following mTBI is associated with behavioral markers of attention, particularly cognitively driven pupillary dilation responses and eye movement patterns. Thirty-five adults were recruited. Pupillary responses and eye movements were tracked while participants performed a MOT task in which the duration of tracking (five and ten seconds), number of target dots (three, four, and five), and number of distractor dots (three, six, and nine) were independent variables. Patients with mTBI had reduced pupil dilation when tracking a high number of target dots (four dots: Mean difference [MD] = 0.79, p < 0.001; five dots: MD = 0.67, p < 0.001) compared to controls. Similarly, patients with mTBI had reduced pupil dilation when the number of distractor dots increased (six distractors: MD = 0.43, p < 0.001; nine distractors: MD = 0.46, p < 0.001) compared to controls. A reduction in pupil dilation observed in patients with mTBI may reflect a limitation in the mental capacity to meet increasing cognitive demands. Eye movement analysis showed that patients with mTBI made significantly more fixations (and with reduced fixation durations), consistent with a local tracking strategy, than controls. In conclusion, tracking pupil response and eye movements while tracking multiple moving objects provided an indication of possible factors that contributed to the poor performance among patients with mTBI.
期刊介绍:
Exploring all aspects of biological visual function, including spatial vision, perception,
low vision, color vision and more, spanning the fields of neuroscience, psychology and psychophysics.