生物牙牙素在儿童未成熟牙拔尖中的应用综述。

Q3 Dentistry
Liz M Gerard, Sumit Gaur
{"title":"生物牙牙素在儿童未成熟牙拔尖中的应用综述。","authors":"Liz M Gerard, Sumit Gaur","doi":"10.5005/jp-journals-10005-3128","DOIUrl":null,"url":null,"abstract":"<p><strong>Aims and background: </strong>Apexification induces calcified barrier formation to retain an immature necrotic permanent tooth. Treating these teeth is often challenging due to thin, fragile walls that are difficult to prepare effectively. Bioactive cement mineral trioxide aggregate (MTA) and recently introduced Biodentine have been applied in the apexification of necrotic immature teeth. This article aims to review the application of Biodentine for the apexification of immature teeth of children.</p><p><strong>Materials and methods: </strong>About 18 studies, both <i>in vitro</i> (<i>n</i> = 15) and randomized controlled clinical trials (RCT) (<i>n</i> = 3), were obtained after a thorough search in online databases such as MEDLINE (PubMed), Scopus, Embase, and Web of Science.</p><p><strong>Results: </strong>The <i>in vitro</i> studies evaluated and compared the fracture resistance and the seal of the apical plug of Biodentine, MTA, and calcium hydroxide (Ca(OH)<sub>2</sub>). The RCTs evaluated the effect of these cements in forming apical plugs and periradicular healing in children's immature, necrotic, and permanent teeth. The studies showed contrary results for fracture resistance and apical seal, with some reporting better outcomes for MTA than Biodentine, while others showed similar outcomes. <i>In vivo</i> studies revealed that both types of cement produced satisfactory periradicular healing with the formation of an apical barrier and periradicular bone. Their effects were more promising than Ca(OH)<sub>2</sub>.</p><p><strong>Conclusion: </strong>Although MTA was superior to Biodentine in the apexification procedure, the latter has advantages such as lower setting time, which makes it ideal for single-visit treatment, which is advantageous in children. Further, long-term clinical trials are required to confirm Biodentine and MTA efficacy in the apexification of immature necrotic teeth.</p><p><strong>Clinical significance: </strong>Biodentine is a promising material for the apexification of immature teeth in children. Its shorter setting time reduces the need for multiple appointments and increases patient compliance.</p><p><strong>How to cite this article: </strong>Gerard LM, Gaur S. Application of Biodentine for Apexification of Immature Teeth of Children: A Scoping Review. Int J Clin Pediatr Dent 2025;18(5):573-579.</p>","PeriodicalId":36045,"journal":{"name":"International Journal of Clinical Pediatric Dentistry","volume":"18 5","pages":"573-579"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12488514/pdf/","citationCount":"0","resultStr":"{\"title\":\"Application of Biodentine for Apexification of Immature Teeth of Children: A Scoping Review.\",\"authors\":\"Liz M Gerard, Sumit Gaur\",\"doi\":\"10.5005/jp-journals-10005-3128\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aims and background: </strong>Apexification induces calcified barrier formation to retain an immature necrotic permanent tooth. Treating these teeth is often challenging due to thin, fragile walls that are difficult to prepare effectively. Bioactive cement mineral trioxide aggregate (MTA) and recently introduced Biodentine have been applied in the apexification of necrotic immature teeth. This article aims to review the application of Biodentine for the apexification of immature teeth of children.</p><p><strong>Materials and methods: </strong>About 18 studies, both <i>in vitro</i> (<i>n</i> = 15) and randomized controlled clinical trials (RCT) (<i>n</i> = 3), were obtained after a thorough search in online databases such as MEDLINE (PubMed), Scopus, Embase, and Web of Science.</p><p><strong>Results: </strong>The <i>in vitro</i> studies evaluated and compared the fracture resistance and the seal of the apical plug of Biodentine, MTA, and calcium hydroxide (Ca(OH)<sub>2</sub>). The RCTs evaluated the effect of these cements in forming apical plugs and periradicular healing in children's immature, necrotic, and permanent teeth. The studies showed contrary results for fracture resistance and apical seal, with some reporting better outcomes for MTA than Biodentine, while others showed similar outcomes. <i>In vivo</i> studies revealed that both types of cement produced satisfactory periradicular healing with the formation of an apical barrier and periradicular bone. Their effects were more promising than Ca(OH)<sub>2</sub>.</p><p><strong>Conclusion: </strong>Although MTA was superior to Biodentine in the apexification procedure, the latter has advantages such as lower setting time, which makes it ideal for single-visit treatment, which is advantageous in children. Further, long-term clinical trials are required to confirm Biodentine and MTA efficacy in the apexification of immature necrotic teeth.</p><p><strong>Clinical significance: </strong>Biodentine is a promising material for the apexification of immature teeth in children. Its shorter setting time reduces the need for multiple appointments and increases patient compliance.</p><p><strong>How to cite this article: </strong>Gerard LM, Gaur S. Application of Biodentine for Apexification of Immature Teeth of Children: A Scoping Review. Int J Clin Pediatr Dent 2025;18(5):573-579.</p>\",\"PeriodicalId\":36045,\"journal\":{\"name\":\"International Journal of Clinical Pediatric Dentistry\",\"volume\":\"18 5\",\"pages\":\"573-579\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12488514/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Clinical Pediatric Dentistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5005/jp-journals-10005-3128\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/25 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"Dentistry\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Clinical Pediatric Dentistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5005/jp-journals-10005-3128","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/25 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"Dentistry","Score":null,"Total":0}
引用次数: 0

摘要

目的和背景:尖化诱导钙化屏障形成以保留未成熟坏死的恒牙。治疗这些牙齿往往是具有挑战性的,因为薄而脆弱的牙壁,很难有效地准备。生物活性水泥矿物三氧化物骨料(MTA)和最近引进的生物牙本质已被应用于坏死未成熟牙齿的尖化。本文就生物牙定剂在儿童未成熟牙拔尖中的应用进行综述。材料与方法:通过MEDLINE (PubMed)、Scopus、Embase、Web of Science等在线数据库的全面检索,获得体外实验(n = 15)和随机对照临床试验(RCT) (n = 3)共18项研究。结果:体外研究评估并比较了Biodentine、MTA和氢氧化钙(Ca(OH)2)的抗骨折性和根尖塞的密封性。随机对照试验评估了这些骨水泥在儿童未成熟、坏死和恒牙的根尖塞形成和根周愈合中的作用。研究显示抗骨折性和根尖密封的结果相反,一些研究报告MTA的结果比Biodentine好,而另一些研究显示类似的结果。体内研究表明,两种类型的骨水泥均能产生满意的根周愈合,形成根尖屏障和根周骨。它们的效果比Ca(OH)2更有希望。结论:MTA虽然在根尖治疗中优于生物牙定,但生物牙定具有固定时间短的优点,适合单次就诊,对儿童有利。此外,还需要长期的临床试验来证实生物牙妥定和MTA在未成熟坏死牙尖化中的疗效。临床意义:生物牙本质是一种很有前途的儿童未成熟牙尖化材料。其较短的设置时间减少了多次预约的需要,并提高了患者的依从性。本文引用本文:李晓明,高涛。生物牙定剂在儿童未成熟牙拔尖中的应用综述。中华临床儿科杂志,2015;18(5):573-579。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Application of Biodentine for Apexification of Immature Teeth of Children: A Scoping Review.

Application of Biodentine for Apexification of Immature Teeth of Children: A Scoping Review.

Aims and background: Apexification induces calcified barrier formation to retain an immature necrotic permanent tooth. Treating these teeth is often challenging due to thin, fragile walls that are difficult to prepare effectively. Bioactive cement mineral trioxide aggregate (MTA) and recently introduced Biodentine have been applied in the apexification of necrotic immature teeth. This article aims to review the application of Biodentine for the apexification of immature teeth of children.

Materials and methods: About 18 studies, both in vitro (n = 15) and randomized controlled clinical trials (RCT) (n = 3), were obtained after a thorough search in online databases such as MEDLINE (PubMed), Scopus, Embase, and Web of Science.

Results: The in vitro studies evaluated and compared the fracture resistance and the seal of the apical plug of Biodentine, MTA, and calcium hydroxide (Ca(OH)2). The RCTs evaluated the effect of these cements in forming apical plugs and periradicular healing in children's immature, necrotic, and permanent teeth. The studies showed contrary results for fracture resistance and apical seal, with some reporting better outcomes for MTA than Biodentine, while others showed similar outcomes. In vivo studies revealed that both types of cement produced satisfactory periradicular healing with the formation of an apical barrier and periradicular bone. Their effects were more promising than Ca(OH)2.

Conclusion: Although MTA was superior to Biodentine in the apexification procedure, the latter has advantages such as lower setting time, which makes it ideal for single-visit treatment, which is advantageous in children. Further, long-term clinical trials are required to confirm Biodentine and MTA efficacy in the apexification of immature necrotic teeth.

Clinical significance: Biodentine is a promising material for the apexification of immature teeth in children. Its shorter setting time reduces the need for multiple appointments and increases patient compliance.

How to cite this article: Gerard LM, Gaur S. Application of Biodentine for Apexification of Immature Teeth of Children: A Scoping Review. Int J Clin Pediatr Dent 2025;18(5):573-579.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
1.20
自引率
0.00%
发文量
135
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信