心脏代谢指数(CMI)与绝经后抑郁症的相关性:基于NHANES 2005-2018的横断面研究

IF 1.4 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Changxing Liu, Zhirui Zhang, Tianwei Meng, Chengjia Li, Boyu Wang, Xiyin Guo, Jia Chen, He Wang, Zhiping Liu
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引用次数: 0

摘要

绝经后女性患抑郁症的风险显著增加。因此,及早发现并干预绝经后抑郁症尤为重要。本研究的目的是评估绝经后妇女心脏代谢指数(CMI)与抑郁之间的关系。通过收集2005-2018年国家健康与营养检查调查(NHANES)的信息,进行了一项横断面研究。采用多元线性回归模型探讨绝经后妇女CMI与抑郁的关系。使用阈值效应分析和拟合的平滑曲线来描述非线性关联。此外,还进行了相互作用试验和亚组分析。共956人参加本研究,平均年龄为64.67±9.17岁。在完全校正的模型中,CMI与绝经后抑郁呈正相关[OR = 1.35 (1.05, 1.77), p = 0.0202]。我们的研究发现,CMI较高的绝经后妇女患抑郁症的风险更大。亚组分析发现,在经历过中风和怀孕次数较多的绝经后妇女中,CMI与抑郁症之间存在更强的正相关(相互作用P < 0.05)。我们发现绝经后抑郁与CMI之间存在非线性关联(P为对数似然比)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Correlation of cardiometabolic index (CMI) with postmenopausal depression: a cross-sectional study based on NHANES 2005-2018.

The risk of depression increases significantly in women after menopause. Therefore, it is particularly important to identify and intervene early in postmenopausal depression. The aim of this study was to assess the relationship between cardiometabolic index (CMI) and depression in postmenopausal women. A cross-sectional study was conducted by collecting information from the 2005-2018 National Health and Nutrition Examination Survey (NHANES). Multiple linear regression models were used to investigate the association between CMI and depression among postmenopausal women. Threshold effects analyses and fitted smoothed curves were used to describe nonlinear associations. In addition, interaction tests and subgroup analyses were performed.A total of 956 individuals participated in this study and their mean age was 64.67 ± 9.17 years. CMI was positively associated with postmenopausal depression in a fully corrected model [OR = 1.35 (1.05, 1.77), p = .0202]. Our study found that postmenopausal women with higher CMI were at greater risk of depression. Subgroup analyses found a stronger positive correlation between CMI and depression in postmenopausal women who had experienced a stroke and a higher number of pregnancies (P for interaction < 0.05).We found a non-linear association between postmenopausal depression and CMI (P for log likelihood ratio < 0.05). In addition, our study found that CMI was a better predictor of postmenopausal depression than WWI.Increased CMI is associated with an increased risk of postmenopausal depression.CMI can be used as a new anthropometric measure for predicting postmenopausal depression with greater predictive power than the WWI.

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来源期刊
Women & Health
Women & Health Multiple-
CiteScore
2.70
自引率
0.00%
发文量
73
期刊介绍: Women & Health publishes original papers and critical reviews containing highly useful information for researchers, policy planners, and all providers of health care for women. These papers cover findings from studies concerning health and illness and physical and psychological well-being of women, as well as the environmental, lifestyle and sociocultural factors that are associated with health and disease, which have implications for prevention, early detection and treatment, limitation of disability and rehabilitation.
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