Inhibition of butyrylcholinesterase in a population exposed to insecticides during a campaign against Aedes aegypti.

Background: Chemical control remains a widely used strategy to reduce morbidity from vector-borne diseases such as dengue. However, the potential health risks to exposed populations necessitates ongoing monitoring, particularly due to the toxicity and volume of insecticides employed.

Methods: This study assessed butyrylcholinesterase activity in residents of a city in southern Mexico during distinct periods of exposure to carbamate and organophosphate insecticides.

Results: A statistically significant inhibition of enzymatic activity was observed during the rainy season, which coincided with an increase in insecticide application.

Conclusions: These findings highlight the need for public health authorities to implement preventative measures aimed at minimizing poisoning risks associated with vector control activities.