{"title":"胃肠超声造影剂充盈法对老年胃肿瘤和溃疡的鉴别诊断价值。","authors":"Yuanyuan Sun, Yujie Deng, Lin Sang, Qian Zhang","doi":"10.2147/IJGM.S534027","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the differential diagnostic value of the gastrointestinal ultrasound contrast filling method in distinguishing gastric tumors from gastric ulcers in elderly patients.</p><p><strong>Methods: </strong>We retrospectively analyzed 274 elderly patients diagnosed with gastric diseases between January 2022 and October 2024, confirmed by endoscopic pathology as gastric tumors (n=82) or gastric ulcers (n=192). All underwent gastrointestinal ultrasound contrast filling. Differences in conventional ultrasound features (internal echo, calcification, morphology, classification) and contrast-enhanced ultrasound parameters [enhancement intensity (EI), time to peak (TTP), area under curve (AUC), arrival time (AT)] were compared. Spearman correlation assessed parameter-tumor relationships. ROC curves evaluated diagnostic performance.</p><p><strong>Results: </strong>The tumor group showed higher rates of low internal echo, calcification, irregular morphology, and type II classification than the ulcer group (P<0.05). EI, TTP, AUC, and AT were significantly elevated in tumors (P<0.05), correlating positively with tumor occurrence (r=0.524-0.597, P<0.05). ROC analysis yielded an AUC of 0.947, with sensitivity 96.72% and specificity 98.91%.</p><p><strong>Conclusion: </strong>Gastrointestinal ultrasound contrast filling effectively demonstrates both conventional and enhancement features of gastric lesions in the elderly, providing high sensitivity and specificity for differentiating gastric tumors from gastric ulcers.</p>","PeriodicalId":14131,"journal":{"name":"International Journal of General Medicine","volume":"18 ","pages":"5939-5947"},"PeriodicalIF":2.0000,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12493100/pdf/","citationCount":"0","resultStr":"{\"title\":\"Differential Diagnostic Value of Gastrointestinal Ultrasound Contrast Filling Method in Differentiating Gastric Tumors and Ulcers in the Elderly.\",\"authors\":\"Yuanyuan Sun, Yujie Deng, Lin Sang, Qian Zhang\",\"doi\":\"10.2147/IJGM.S534027\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To evaluate the differential diagnostic value of the gastrointestinal ultrasound contrast filling method in distinguishing gastric tumors from gastric ulcers in elderly patients.</p><p><strong>Methods: </strong>We retrospectively analyzed 274 elderly patients diagnosed with gastric diseases between January 2022 and October 2024, confirmed by endoscopic pathology as gastric tumors (n=82) or gastric ulcers (n=192). All underwent gastrointestinal ultrasound contrast filling. Differences in conventional ultrasound features (internal echo, calcification, morphology, classification) and contrast-enhanced ultrasound parameters [enhancement intensity (EI), time to peak (TTP), area under curve (AUC), arrival time (AT)] were compared. Spearman correlation assessed parameter-tumor relationships. ROC curves evaluated diagnostic performance.</p><p><strong>Results: </strong>The tumor group showed higher rates of low internal echo, calcification, irregular morphology, and type II classification than the ulcer group (P<0.05). EI, TTP, AUC, and AT were significantly elevated in tumors (P<0.05), correlating positively with tumor occurrence (r=0.524-0.597, P<0.05). ROC analysis yielded an AUC of 0.947, with sensitivity 96.72% and specificity 98.91%.</p><p><strong>Conclusion: </strong>Gastrointestinal ultrasound contrast filling effectively demonstrates both conventional and enhancement features of gastric lesions in the elderly, providing high sensitivity and specificity for differentiating gastric tumors from gastric ulcers.</p>\",\"PeriodicalId\":14131,\"journal\":{\"name\":\"International Journal of General Medicine\",\"volume\":\"18 \",\"pages\":\"5939-5947\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2025-09-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12493100/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of General Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2147/IJGM.S534027\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of General Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2147/IJGM.S534027","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Differential Diagnostic Value of Gastrointestinal Ultrasound Contrast Filling Method in Differentiating Gastric Tumors and Ulcers in the Elderly.
Objective: To evaluate the differential diagnostic value of the gastrointestinal ultrasound contrast filling method in distinguishing gastric tumors from gastric ulcers in elderly patients.
Methods: We retrospectively analyzed 274 elderly patients diagnosed with gastric diseases between January 2022 and October 2024, confirmed by endoscopic pathology as gastric tumors (n=82) or gastric ulcers (n=192). All underwent gastrointestinal ultrasound contrast filling. Differences in conventional ultrasound features (internal echo, calcification, morphology, classification) and contrast-enhanced ultrasound parameters [enhancement intensity (EI), time to peak (TTP), area under curve (AUC), arrival time (AT)] were compared. Spearman correlation assessed parameter-tumor relationships. ROC curves evaluated diagnostic performance.
Results: The tumor group showed higher rates of low internal echo, calcification, irregular morphology, and type II classification than the ulcer group (P<0.05). EI, TTP, AUC, and AT were significantly elevated in tumors (P<0.05), correlating positively with tumor occurrence (r=0.524-0.597, P<0.05). ROC analysis yielded an AUC of 0.947, with sensitivity 96.72% and specificity 98.91%.
Conclusion: Gastrointestinal ultrasound contrast filling effectively demonstrates both conventional and enhancement features of gastric lesions in the elderly, providing high sensitivity and specificity for differentiating gastric tumors from gastric ulcers.
期刊介绍:
The International Journal of General Medicine is an international, peer-reviewed, open access journal that focuses on general and internal medicine, pathogenesis, epidemiology, diagnosis, monitoring and treatment protocols. The journal is characterized by the rapid reporting of reviews, original research and clinical studies across all disease areas.
A key focus of the journal is the elucidation of disease processes and management protocols resulting in improved outcomes for the patient. Patient perspectives such as satisfaction, quality of life, health literacy and communication and their role in developing new healthcare programs and optimizing clinical outcomes are major areas of interest for the journal.
As of 1st April 2019, the International Journal of General Medicine will no longer consider meta-analyses for publication.