完全房室传导阻滞作为类风湿关节炎的心脏并发症:一个罕见的病例报告。

IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL
Acta medica Indonesiana Pub Date : 2025-07-01
Christian Johan, Fatih Anfasa, Adityo Susilo, Johanda Damanik, Rudy Hidayat, Sumariyono Sumariyono, Rm Suryo Anggoro Kusumo Wibowo, Anna Ariane, Faisal Parlindungan, Abirianty Priandani Araminta
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引用次数: 0

摘要

房室传导阻滞(AVB)是类风湿性关节炎(RA)的罕见并发症。RA患者完全AVB显著增加心血管发病率,并使死亡风险增加一倍。我们报告一位48岁的女性,以呼吸困难和外周水肿为主要表现,并伴有3年多关节炎的症状。物理表现包括心动过缓、双侧罗音和与类风湿关节炎一致的手指畸形。心电图表现为完全性AVB,胸部计算机断层扫描显示纤维化、支气管扩张和部分肺不张的马赛克外观。进一步的检查显示c反应蛋白、类风湿因子和几种炎症细胞因子水平升高。暂时植入永久性起搏器,同时进行药物治疗,包括静脉注射(IV)甲基强的松龙脉冲治疗和静脉注射托珠单抗。RA累及心脏通常表现为心包积液、心力衰竭、心肌炎和冠状动脉疾病。完全性AVB是一种罕见但重要的关节外病变,需要早期识别并使用起搏器、抗炎药物和改善疾病的抗风湿药物进行治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Complete Atrioventricular (AV) Block as a Cardiac Complication of Rheumatoid Arthritis: A Rare Case Report.

Atrioventricular block (AVB) is a rare complication of rheumatoid arthritis (RA). Complete AVB in people with RA significantly increases cardiovascular morbidity and doubles the mortality risk. We report on a 48-year-old woman presenting with dyspnea and peripheral edema, with symptoms of polyarthritis for 3 years. Physical findings included bradycardia, bilateral rales, and finger deformities consistent with RA. Electrocardiography featured complete AVB, and a thoracic computed tomography scan showed a mosaic appearance with fibrosis, bronchiectasis, and partial atelectasis of the lungs. Further tests showed elevated levels of C-reactive protein, rheumatoid factor, and several inflammatory cytokines. Transient followed by permanent pacemaker placement was performed along with pharmacological treatments, including intravenous (IV) methylprednisolone pulse therapy and IV tocilizumab. Cardiac involvement in RA usually takes the form of pericardial effusion, heart failure, myocarditis, and coronary artery disease. Complete AVB is a rare but important extra-articular involvement in RA that warrants early recognition and treatment with a pacemaker, anti-inflammatory drugs, and disease-modifying antirheumatic drugs.

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来源期刊
Acta medica Indonesiana
Acta medica Indonesiana MEDICINE, GENERAL & INTERNAL-
CiteScore
2.30
自引率
0.00%
发文量
61
审稿时长
12 weeks
期刊介绍: Acta Medica Indonesiana – The Indonesian Journal of Internal Medicine is an open accessed online journal and comprehensive peer-reviewed medical journal published by the Indonesian Society of Internal Medicine since 1968. Our main mission is to encourage the novel and important science in the clinical area in internal medicine. We welcome authors for original articles (research), review articles, interesting case reports, special articles, clinical practices, and medical illustrations that focus on the clinical area of internal medicine. Subjects suitable for publication include, but are not limited to the following fields of: -Allergy and immunology -Emergency medicine -Cancer and stem cells -Cardiovascular -Endocrinology and Metabolism -Gastroenterology -Gerontology -Hematology -Hepatology -Tropical and Infectious Disease -Virology -Internal medicine -Psychosomatic -Pulmonology -Rheumatology -Renal and Hypertension -Thyroid
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