{"title":"在南非豪登省的一家南非三级医院建立成人胸部CT检查的当地诊断参考水平。","authors":"Mpumelelo Nyathi","doi":"10.1016/j.apradiso.2025.112207","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Computed tomography (CT) provides high-resolution three-dimensional images. However, there are concerns that CT delivers high patient doses. To mitigate risks, the International Commission on Radiological Protection introduced Diagnostic Reference Levels (DRLs) aimed at optimization of doses while maintaining acceptable image quality. This study established local DRLs for adult chest CT scans using dose length product (DLP) and volumetric CT dose index (CTDI<sub>vol</sub>) doses at a tertiary hospital.</p><p><strong>Materials and methods: </strong>A retrospective review of CTDI<sub>vol</sub> and DLP values for 50 patients (≥18 years, weighing 70 ± 10 kg) who underwent non-contrast chest CT examinations. CT scan parameters were also documented. Median CTDI<sub>vol</sub> and DLP doses were calculated as local DRLs, while the 75th percentile values were proposed as national DRLs for benchmarking with international studies. Independent samples t-test compared dose metrics between male and female patients. Statistical significance was set at p < 0.05.</p><p><strong>Results: </strong>The median CTDI<sub>vol</sub> values were 9.5 mGy and 10.8 mGy for females and males respectively (p = 0.18) while respective median DLP values were 370.8 mGy cm and 447.6 mGy cm (p = 0.02). The established local DRLs in terms of CTDI<sub>vol</sub> and DLP were 10.4 mGy and 428.9 mGy cm respectively while the respective proposed national DRLs were 14.4 mGy and 622.2 mGy cm. CTDI<sub>vol</sub> values were comparable to international DRLs while DLP values were higher.</p><p><strong>Conclusion: </strong>The established local DRLs provide a baseline for optimizing adult chest CT practices at our institution and a first step toward establishment of national DRL standards in South Africa.</p>","PeriodicalId":8096,"journal":{"name":"Applied Radiation and Isotopes","volume":"226 ","pages":"112207"},"PeriodicalIF":1.8000,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Establishment of local diagnostic reference levels for adult chest CT examinations at a South African tertiary hospital in Gauteng province, South Africa.\",\"authors\":\"Mpumelelo Nyathi\",\"doi\":\"10.1016/j.apradiso.2025.112207\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Computed tomography (CT) provides high-resolution three-dimensional images. However, there are concerns that CT delivers high patient doses. To mitigate risks, the International Commission on Radiological Protection introduced Diagnostic Reference Levels (DRLs) aimed at optimization of doses while maintaining acceptable image quality. This study established local DRLs for adult chest CT scans using dose length product (DLP) and volumetric CT dose index (CTDI<sub>vol</sub>) doses at a tertiary hospital.</p><p><strong>Materials and methods: </strong>A retrospective review of CTDI<sub>vol</sub> and DLP values for 50 patients (≥18 years, weighing 70 ± 10 kg) who underwent non-contrast chest CT examinations. CT scan parameters were also documented. Median CTDI<sub>vol</sub> and DLP doses were calculated as local DRLs, while the 75th percentile values were proposed as national DRLs for benchmarking with international studies. Independent samples t-test compared dose metrics between male and female patients. Statistical significance was set at p < 0.05.</p><p><strong>Results: </strong>The median CTDI<sub>vol</sub> values were 9.5 mGy and 10.8 mGy for females and males respectively (p = 0.18) while respective median DLP values were 370.8 mGy cm and 447.6 mGy cm (p = 0.02). The established local DRLs in terms of CTDI<sub>vol</sub> and DLP were 10.4 mGy and 428.9 mGy cm respectively while the respective proposed national DRLs were 14.4 mGy and 622.2 mGy cm. CTDI<sub>vol</sub> values were comparable to international DRLs while DLP values were higher.</p><p><strong>Conclusion: </strong>The established local DRLs provide a baseline for optimizing adult chest CT practices at our institution and a first step toward establishment of national DRL standards in South Africa.</p>\",\"PeriodicalId\":8096,\"journal\":{\"name\":\"Applied Radiation and Isotopes\",\"volume\":\"226 \",\"pages\":\"112207\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2025-09-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Applied Radiation and Isotopes\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1016/j.apradiso.2025.112207\",\"RegionNum\":3,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, INORGANIC & NUCLEAR\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Radiation and Isotopes","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1016/j.apradiso.2025.112207","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
Establishment of local diagnostic reference levels for adult chest CT examinations at a South African tertiary hospital in Gauteng province, South Africa.
Introduction: Computed tomography (CT) provides high-resolution three-dimensional images. However, there are concerns that CT delivers high patient doses. To mitigate risks, the International Commission on Radiological Protection introduced Diagnostic Reference Levels (DRLs) aimed at optimization of doses while maintaining acceptable image quality. This study established local DRLs for adult chest CT scans using dose length product (DLP) and volumetric CT dose index (CTDIvol) doses at a tertiary hospital.
Materials and methods: A retrospective review of CTDIvol and DLP values for 50 patients (≥18 years, weighing 70 ± 10 kg) who underwent non-contrast chest CT examinations. CT scan parameters were also documented. Median CTDIvol and DLP doses were calculated as local DRLs, while the 75th percentile values were proposed as national DRLs for benchmarking with international studies. Independent samples t-test compared dose metrics between male and female patients. Statistical significance was set at p < 0.05.
Results: The median CTDIvol values were 9.5 mGy and 10.8 mGy for females and males respectively (p = 0.18) while respective median DLP values were 370.8 mGy cm and 447.6 mGy cm (p = 0.02). The established local DRLs in terms of CTDIvol and DLP were 10.4 mGy and 428.9 mGy cm respectively while the respective proposed national DRLs were 14.4 mGy and 622.2 mGy cm. CTDIvol values were comparable to international DRLs while DLP values were higher.
Conclusion: The established local DRLs provide a baseline for optimizing adult chest CT practices at our institution and a first step toward establishment of national DRL standards in South Africa.
期刊介绍:
Applied Radiation and Isotopes provides a high quality medium for the publication of substantial, original and scientific and technological papers on the development and peaceful application of nuclear, radiation and radionuclide techniques in chemistry, physics, biochemistry, biology, medicine, security, engineering and in the earth, planetary and environmental sciences, all including dosimetry. Nuclear techniques are defined in the broadest sense and both experimental and theoretical papers are welcome. They include the development and use of α- and β-particles, X-rays and γ-rays, neutrons and other nuclear particles and radiations from all sources, including radionuclides, synchrotron sources, cyclotrons and reactors and from the natural environment.
The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria.
Papers dealing with radiation processing, i.e., where radiation is used to bring about a biological, chemical or physical change in a material, should be directed to our sister journal Radiation Physics and Chemistry.