腭裂修复后全球口鼻瘘发生率的增加：对报道的瘘率的系统回顾和荟萃分析。

IF 1.3 4区医学 Q2 Dentistry

Cleft Palate-Craniofacial Journal Pub Date : 2025-10-03 DOI:10.1177/10556656251382537

Isabel A Ryan, Nicholas A Han, Ashley E Chang, Alvin B Yu, Philip D Tolley, Allison C Hu, Oksana A Jackson, Scott P Bartlett, Jesse A Taylor, Jordan W Swanson

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引用次数: 0

摘要

目的探讨初级腭成形术后口鼻瘘（ONF）的发生率可能受到技术改进和护理扩大的影响。我们评估了ONF的时空格局。本研究对1960年1月至2024年11月间报道腭裂修复术后瘘管率的出版物进行了系统回顾和荟萃分析。腭裂患者。InterventionsPrimary腭成形术。主要观察指标：瘘管率。结果共纳入223篇文献，71238例患者。中位瘘发生率从20世纪60年代（13.9%,n = 2）到21世纪初（4.9%,IQR: 2.9%-11.0%）下降。瘘管率在2010年代显著增加（6.7%,IQR: 2.6-14.0%），并在2020年代继续增加（10.7%,IQR: 5.7-20.5%, p = 0.005）。欧洲国家的瘘管病发病率从21世纪初（4.4%,IQR: 2.0-12.5%）到21世纪20年代（21.1%,IQR: 12.7-49.4%, p = 0.041）增长最快。从20世纪60年代到21世纪初，报道的瘘管发病率有所下降，但此后又有所增加。

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Global Increase in Oronasal Fistula Rates Following Cleft Palate Repair: A Systematic Review and Meta-Analysis of Reported Fistula Rates.

ObjectiveOronasal fistula (ONF) rates after primary palatoplasty may be influenced by technique improvements and care expansion. We evaluated the temporal and geospatial patterns of ONF.DesignA systematic review and meta-analysis were performed of publications between January 1960 and November 2024 that reported fistula rate following cleft palate repair.SettingN/A.PatientsPatients with cleft palate.InterventionsPrimary palatoplasty.Main Outcome Measure(s)Fistula rate.Results223 publications with 71,238 patients were included. Median fistula rates decreased from the 1960s (13.9%, n = 2) to the 2000s (4.9%, IQR: 2.9%-11.0%). Fistula rates increased significantly in the 2010s (6.7%, IQR: 2.6-14.0%), and continued to increase in the 2020s (10.7%, IQR: 5.7-20.5%, p = 0.005). Fistula rates among European nations showed the largest increase from the 2000s (4.4%, IQR: 2.0-12.5%) to the 2020s (21.1%, IQR: 12.7-49.4%, p = 0.041).ConclusionsReported fistula incidence declined from reports in the 1960s through the 2000s but has since increased.

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来源期刊

Cleft Palate-Craniofacial Journal DENTISTRY, ORAL SURGERY & MEDICINE-SURGERY

CiteScore

2.20

自引率

36.40%

发文量

审稿时长

4-8 weeks

期刊介绍： The Cleft Palate-Craniofacial Journal (CPCJ) is the premiere peer-reviewed, interdisciplinary, international journal dedicated to current research on etiology, prevention, diagnosis, and treatment in all areas pertaining to craniofacial anomalies. CPCJ reports on basic science and clinical research aimed at better elucidating the pathogenesis, pathology, and optimal methods of treatment of cleft and craniofacial anomalies. The journal strives to foster communication and cooperation among professionals from all specialties.