A Ibba, A Rosa, A Fais, B Era, S Porcedda, A Piras
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Fatty acid profile and biological activity of supercritical fluid extract of Rosa canina L. seeds.
The study concerns the extraction by supercritical carbon dioxide, from the seeds of Rosa canina L. Extraction experiments were carried out at a pressure of 300 bar and a temperature of 40 °C, SFE[300:40]. Analyses by GC-FID and HPLC-DAD of the extract showed elevated levels of linoleic acid, 18:2 n-6 (54.7%) and linolenic acid 18:3 n-3 (19.8%). The sample SFE[300:40] was compared with that obtained using n-hexane in a Soxhlet apparatus, (Sx). The antioxidant properties determined by the ABTS test, showed that SFE[300:40] and Sx had EC50 = (0.34 ± 0.01) mg/mL, and no activity, respectively. The total phenolic content, expressed as the concentration of Gallic Acid Equivalents (GAE), in the SFE[300:40] was (16 ± 2 mg/g) and a concentration below the detection limit of the method for the Sx sample. The inhibition percentages against xanthine oxidase were 5% for SFE[300:40] and 12% for Sx extract.
期刊介绍：
The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds.
The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal.
Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section.
All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.
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