1.5 t、3 t和7 t时心脏磁共振心电图信号的定量混杂分析——评估标准化电极位置和序列类型——迈向质量保证。

IF 3.5 2区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Richard Hickstein, Stephanie Wiesemann, Darian Viezzer, Denise Kleindienst, Teodora Chitiboi, Bogdan Andrei Gheorghita, Jens Wetzl, Thomas Hadler, Sebastian Dietrich, Sebastian Schmitter, Jeanette Schulz-Menger
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引用次数: 0

摘要

背景:在心脏MRI中用于门控的心电图(ECG)可能受到扫描仪孔内多个混杂因素的影响。目的:量化磁场强度(1.5 T/ 3t / 7t)、标准化电极位置和成像序列对用于门控的心电信号的影响。研究类型:前瞻性。人群:健康志愿者16人(男性8人,平均年龄26.25±7.67岁)。场强/序列:平衡稳态自由进动序列(1.5 T/ 3t)、快速低角度拍摄序列(7 T)、4D流序列(1.5 T/ 3t / 7t)。评估:记录屏气和非屏气短轴扫描(分别为sax-bh和sax-nbh)和1.5 T/3 T/7 T时的4D血流扫描时的心电图信号。在每种场强下使用4个标准化电极定位(pos1-4)重复所有扫描。Pos1/2分别是供应商推荐的1.5 T/3 T/7 T扫描位置,而pos3/4是先前研究中推荐的替代位置。通过qrs特征相关性评估混杂心电图信号与未混杂基线心电图信号的相似性。电影图像质量(IQ)由3名读者(分别有6年、10年和22年的经验)在4分李克特量表上进行评估。统计检验:采用固定效应III型检验的线性混合模型(总体)和在显著性水平p下调整自由度的t检验(两两亚组比较)结果:场强增加导致与基线测量的相似性显著降低,r值(提供95%置信区间)为1.5 t: 97% (92.6-101.3);3 t: 91.4% (87.1-95.8);7 T: 50.4%(46 - 54.9)和较低的智商:1.5 T: 2.33 (2.12 - -2.55);3 t: 1.96 (1.75-2.17);7 t: 0.91(0.7-1.12)。供应商指定的电极位置pos1: 91.8% (87.2-96.5), pos2: 88.3%(83.7-92.9)与基线测量的相关性显著高于替代位置pos3: 67.5%(62.9-72.1)和pos4: 70.8%(66.2-75.4)。评价的标准化序列显示相似的心电图畸变量,r值为:sax-bh: 77.3% (73-81.7);4D: 79.3% (75 ~ 83.7), p = 0.54;Sax-nbh: 82.1% (77.8 ~ 86.5), p = 0.31,但sax-bh与Sax-nbh: 4.8%(2.88 ~ 6.72)差异有统计学意义。数据结论:电场强度增大导致心电信号明显失真。供应商指定的位置1/2比先前出版物中推荐的替代位置3/4导致的ECG信号失真更少。证据等级:2;技术功效:第5阶段。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Quantitative Confounder Analysis of Electrocardiogram Signals in Cardiac Magnetic Resonance at 1.5, 3 and 7 T-Assessing Standardized Electrode Positions and Sequence Types-Towards Quality Assurance.

Background: The electrocardiogram (ECG) used for gating in cardiac MRI may be compromised by multiple confounders inside the scanner bore.

Purpose: To quantify the influence of magnetic field strengths (1.5 T/3 T/7 T), standardized electrode positions, and imaging sequences on ECG signals used for gating.

Study type: Prospective.

Population: Sixteen healthy volunteers (eight male; mean age 26.25 ± 7.67 years).

Field strength/sequence: Balanced steady-state free precession cine (1.5 T/3 T), fast low-angle shot cine (7 T), and 4D flow (1.5 T/3 T/7 T) sequences.

Assessment: ECG-signals were recorded during breath-hold and non-breath-hold short axis cine (sax-bh and sax-nbh, respectively) and 4D flow scans at 1.5 T/3 T/7 T. All scans were repeated with 4 standardized electrode positionings (pos1-4) at each field strength. Pos1/2 were vendor-recommended positionings for 1.5 T/3 T/7 T scans, respectively, whereas pos3/4 were alternative positionings recommended in previous studies. Similarity between confounded ECG-signals and unconfounded baseline ECG-signals was assessed by QRS-feature correlation. Cine image quality (IQ) was assessed by 3 readers (with 6, 10, and 22 years experience) on a four-point Likert scale.

Statistical tests: Linear mixed models with type III tests of fixed effects (overall) and t tests with adjusted degrees of freedom (pairwise subgroup-comparisons) at significance level p < 0.05.

Results: Increasing field strength resulted in significantly decreasing similarity to baseline measurements, with r values (provided with 95% confidence interval) of 1.5 T: 97% (92.6-101.3); 3 T: 91.4% (87.1-95.8); 7 T: 50.4% (46-54.9) and lower IQ: 1.5 T: 2.33 (2.12-2.55); 3 T: 1.96 (1.75-2.17); 7 T: 0.91 (0.7-1.12). Vendor-specified electrode positions pos1: 91.8% (87.2-96.5), pos2: 88.3% (83.7-92.9) showed significantly higher correlation with baseline measurements than alternative positions pos3: 67.5% (62.9-72.1) and pos4: 70.8% (66.2-75.4). The evaluated standardized sequences showed similar amounts of electrocardiogram distortion, with r values of: sax-bh: 77.3% (73-81.7); 4D: 79.3% (75-83.7), p = 0.54; sax-nbh: 82.1% (77.8-86.5), p = 0.31, but the difference between sax-bh and sax-nbh: 4.8% (2.88-6.72) was significant.

Data conclusion: Increasing field strength leads to significant ECG signal distortions. Vendor-specified positions 1/2 resulted in less distorted ECG signals than alternative positions 3/4 recommended in previous publications.

Level of evidence: 2:

Technical efficacy: Stage 5.

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来源期刊
CiteScore
9.70
自引率
6.80%
发文量
494
审稿时长
2 months
期刊介绍: The Journal of Magnetic Resonance Imaging (JMRI) is an international journal devoted to the timely publication of basic and clinical research, educational and review articles, and other information related to the diagnostic applications of magnetic resonance.
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