肿瘤病毒的分类及对单纯疱疹病毒、水痘带状疱疹病毒的认识。

IF 6 2区医学 Q1 ONCOLOGY

Cancer Cell International Pub Date : 2025-10-03 DOI:10.1186/s12935-025-03983-9

Amir Ghaemi, Sanaz Sadeh

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引用次数: 0

摘要

尽管这篇题为《溶瘤病毒治疗和病毒致癌基因在癌症干细胞中的作用：癌症干细胞中的病毒综述》的论文提供了关于病毒在癌症生物学中的贡献的信息细节，但它将单纯疱疹病毒（HSV）和水痘带状疱疹病毒（VZV）分类为癌病毒是不准确的。目前的证据表明，虽然HSV和VZV可能在免疫功能低下的癌症患者中重新激活，但这两种病毒与肿瘤发生之间没有因果关系。有必要区分癌症诱导病毒和癌症患者因免疫抑制而产生的再激活病毒。

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Oncovirus classification and insights into herpes simplex virus, Varicella-Zoster virus.

Even though the paper entitled: The role of oncolytic virotherapy and viral oncogenes in the cancer stem cells: a review of virus in cancer stem cells" provides informative details regarding viral contribution in cancer biology, its classification of Herpes Simplex Virus (HSV) and Varicella-Zoster Virus (VZV) as oncoviruses is inaccurate.Current evidence demonstrates that while HSV and VZV may reactivate in immunocompromised cancer patients, there is no causative relationship between these two viruses and oncogenesis. It is necessary to make a distinction between cancer-inducing viruses and reactivated viruses due to immune suppression among cancer patients.

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来源期刊

Cancer Cell International ONCOLOGY-

CiteScore

10.90

自引率

1.70%

发文量

360

审稿时长

1 months

期刊介绍： Cancer Cell International publishes articles on all aspects of cancer cell biology, originating largely from, but not limited to, work using cell culture techniques. The journal focuses on novel cancer studies reporting data from biological experiments performed on cells grown in vitro, in two- or three-dimensional systems, and/or in vivo (animal experiments). These types of experiments have provided crucial data in many fields, from cell proliferation and transformation, to epithelial-mesenchymal interaction, to apoptosis, and host immune response to tumors. Cancer Cell International also considers articles that focus on novel technologies or novel pathways in molecular analysis and on epidemiological studies that may affect patient care, as well as articles reporting translational cancer research studies where in vitro discoveries are bridged to the clinic. As such, the journal is interested in laboratory and animal studies reporting on novel biomarkers of tumor progression and response to therapy and on their applicability to human cancers.