Christoph Mader MD , Marcus Czabanka MD , Elke Hattingen MD , Christophe T. Arendt MD
{"title":"脑卒中样表现的小鞍结节脑膜瘤被皮质类固醇所掩盖:1例报告","authors":"Christoph Mader MD , Marcus Czabanka MD , Elke Hattingen MD , Christophe T. Arendt MD","doi":"10.1016/j.radcr.2025.08.097","DOIUrl":null,"url":null,"abstract":"<div><div>Tuberculum sellae meningiomas are known to cause visual symptoms due to their proximity to the optic apparatus. However, their impact on pituitary function, particularly when the tumor is small, is less frequently described. Although secondary adrenal insufficiency is rare in this context, it may be underrecognized. We report a case in which a small (1.2 cm) tuberculum sellae meningioma resulted in clinically relevant adrenocorticotropin deficiency, unmasked by intra-articular corticosteroid injections. The patient initially presented with nonspecific symptoms and transient ischemic attack-like episodes, which led to imaging and identification of the tumor. Surgical resection of the tumor resulted in complete resolution of symptoms. This case highlights the need for a high index of suspicion for pituitary dysfunction even in small suprasellar tumors and suggests that exogenous corticosteroids may exacerbate underlying hypothalamic-pituitary-adrenal axis compromise.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"20 12","pages":"Pages 6253-6256"},"PeriodicalIF":0.0000,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Stroke-like presentation of a small tuberculum sellae meningioma unmasked by corticosteroid use: A case report\",\"authors\":\"Christoph Mader MD , Marcus Czabanka MD , Elke Hattingen MD , Christophe T. Arendt MD\",\"doi\":\"10.1016/j.radcr.2025.08.097\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Tuberculum sellae meningiomas are known to cause visual symptoms due to their proximity to the optic apparatus. However, their impact on pituitary function, particularly when the tumor is small, is less frequently described. Although secondary adrenal insufficiency is rare in this context, it may be underrecognized. We report a case in which a small (1.2 cm) tuberculum sellae meningioma resulted in clinically relevant adrenocorticotropin deficiency, unmasked by intra-articular corticosteroid injections. The patient initially presented with nonspecific symptoms and transient ischemic attack-like episodes, which led to imaging and identification of the tumor. Surgical resection of the tumor resulted in complete resolution of symptoms. This case highlights the need for a high index of suspicion for pituitary dysfunction even in small suprasellar tumors and suggests that exogenous corticosteroids may exacerbate underlying hypothalamic-pituitary-adrenal axis compromise.</div></div>\",\"PeriodicalId\":53472,\"journal\":{\"name\":\"Radiology Case Reports\",\"volume\":\"20 12\",\"pages\":\"Pages 6253-6256\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-09-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Radiology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1930043325008295\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1930043325008295","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Stroke-like presentation of a small tuberculum sellae meningioma unmasked by corticosteroid use: A case report
Tuberculum sellae meningiomas are known to cause visual symptoms due to their proximity to the optic apparatus. However, their impact on pituitary function, particularly when the tumor is small, is less frequently described. Although secondary adrenal insufficiency is rare in this context, it may be underrecognized. We report a case in which a small (1.2 cm) tuberculum sellae meningioma resulted in clinically relevant adrenocorticotropin deficiency, unmasked by intra-articular corticosteroid injections. The patient initially presented with nonspecific symptoms and transient ischemic attack-like episodes, which led to imaging and identification of the tumor. Surgical resection of the tumor resulted in complete resolution of symptoms. This case highlights the need for a high index of suspicion for pituitary dysfunction even in small suprasellar tumors and suggests that exogenous corticosteroids may exacerbate underlying hypothalamic-pituitary-adrenal axis compromise.
期刊介绍:
The content of this journal is exclusively case reports that feature diagnostic imaging. Categories in which case reports can be placed include the musculoskeletal system, spine, central nervous system, head and neck, cardiovascular, chest, gastrointestinal, genitourinary, multisystem, pediatric, emergency, women''s imaging, oncologic, normal variants, medical devices, foreign bodies, interventional radiology, nuclear medicine, molecular imaging, ultrasonography, imaging artifacts, forensic, anthropological, and medical-legal. Articles must be well-documented and include a review of the appropriate literature.