Diogo Carmali , Eduardo Felício, Sónia Afonso Ramos, António Pinheiro, Alberto Silva, Sara Duarte, Guilherme Bernardo, Filipe Gaboleiro, André Pita, Fernando Ferrito
{"title":"Sienna+®/SentiMag®磁前哨淋巴结活检诊断阴茎鳞状细胞癌1例","authors":"Diogo Carmali , Eduardo Felício, Sónia Afonso Ramos, António Pinheiro, Alberto Silva, Sara Duarte, Guilherme Bernardo, Filipe Gaboleiro, André Pita, Fernando Ferrito","doi":"10.1016/j.eucr.2025.103227","DOIUrl":null,"url":null,"abstract":"<div><div>Penile squamous cell carcinoma (SCC) is a rare malignancy where accurate nodal staging is essential for prognosis and management. Dynamic sentinel lymph node biopsy with radiotracers is the standard approach but requires nuclear medicine facilities and exposes patients to radiation. We report a 62-year-old man with penile SCC who underwent glansectomy with sentinel lymph node biopsy using Sienna+®/SentiMag® and methylene blue. Two sentinel nodes were identified, one exclusively by Sienna+®/SentiMag®. Both were negative for metastasis. This case supports the feasibility of magnetic tracers as a radiation-free alternative in penile cancer staging.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"63 ","pages":"Article 103227"},"PeriodicalIF":0.4000,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Magnetic sentinel node biopsy with Sienna+®/SentiMag® in penile squamous cell carcinoma: Case report\",\"authors\":\"Diogo Carmali , Eduardo Felício, Sónia Afonso Ramos, António Pinheiro, Alberto Silva, Sara Duarte, Guilherme Bernardo, Filipe Gaboleiro, André Pita, Fernando Ferrito\",\"doi\":\"10.1016/j.eucr.2025.103227\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Penile squamous cell carcinoma (SCC) is a rare malignancy where accurate nodal staging is essential for prognosis and management. Dynamic sentinel lymph node biopsy with radiotracers is the standard approach but requires nuclear medicine facilities and exposes patients to radiation. We report a 62-year-old man with penile SCC who underwent glansectomy with sentinel lymph node biopsy using Sienna+®/SentiMag® and methylene blue. Two sentinel nodes were identified, one exclusively by Sienna+®/SentiMag®. Both were negative for metastasis. This case supports the feasibility of magnetic tracers as a radiation-free alternative in penile cancer staging.</div></div>\",\"PeriodicalId\":38188,\"journal\":{\"name\":\"Urology Case Reports\",\"volume\":\"63 \",\"pages\":\"Article 103227\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2025-09-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Urology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2214442025002980\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214442025002980","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
Magnetic sentinel node biopsy with Sienna+®/SentiMag® in penile squamous cell carcinoma: Case report
Penile squamous cell carcinoma (SCC) is a rare malignancy where accurate nodal staging is essential for prognosis and management. Dynamic sentinel lymph node biopsy with radiotracers is the standard approach but requires nuclear medicine facilities and exposes patients to radiation. We report a 62-year-old man with penile SCC who underwent glansectomy with sentinel lymph node biopsy using Sienna+®/SentiMag® and methylene blue. Two sentinel nodes were identified, one exclusively by Sienna+®/SentiMag®. Both were negative for metastasis. This case supports the feasibility of magnetic tracers as a radiation-free alternative in penile cancer staging.