{"title":"嗜血淋巴组织细胞增多症与乙型流感感染的急性呼吸窘迫综合征有关","authors":"Abdelkader Dib , Johny Salem , Mirna Fares","doi":"10.1016/j.hmedic.2025.100379","DOIUrl":null,"url":null,"abstract":"<div><div>We report the case of a 35-year-old woman who presented with fever, diarrhea, and respiratory symptoms, and was found to have acute respiratory distress syndrome (ARDS) in the setting of influenza B infection. Her stay was complicated with disseminated intravascular coagulation and Hemophagocytic lymphohistiocytosis (HLH) confirmed on bone marrow aspirate. Despite multiple therapies including antiviral, corticosteroids, and etoposide, the patient deteriorated and succumbed on day 10 of hospitalization. This case highlights the potential severity of influenza B and the need for early recognition to try and prevent complications such as ARDS and HLH.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"14 ","pages":"Article 100379"},"PeriodicalIF":0.0000,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Hemophagocytic lymphohistiocytosis in association with acute respiratory distress syndrome in the setting of influenza B infection\",\"authors\":\"Abdelkader Dib , Johny Salem , Mirna Fares\",\"doi\":\"10.1016/j.hmedic.2025.100379\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>We report the case of a 35-year-old woman who presented with fever, diarrhea, and respiratory symptoms, and was found to have acute respiratory distress syndrome (ARDS) in the setting of influenza B infection. Her stay was complicated with disseminated intravascular coagulation and Hemophagocytic lymphohistiocytosis (HLH) confirmed on bone marrow aspirate. Despite multiple therapies including antiviral, corticosteroids, and etoposide, the patient deteriorated and succumbed on day 10 of hospitalization. This case highlights the potential severity of influenza B and the need for early recognition to try and prevent complications such as ARDS and HLH.</div></div>\",\"PeriodicalId\":100908,\"journal\":{\"name\":\"Medical Reports\",\"volume\":\"14 \",\"pages\":\"Article 100379\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-09-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2949918625002244\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2949918625002244","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Hemophagocytic lymphohistiocytosis in association with acute respiratory distress syndrome in the setting of influenza B infection
We report the case of a 35-year-old woman who presented with fever, diarrhea, and respiratory symptoms, and was found to have acute respiratory distress syndrome (ARDS) in the setting of influenza B infection. Her stay was complicated with disseminated intravascular coagulation and Hemophagocytic lymphohistiocytosis (HLH) confirmed on bone marrow aspirate. Despite multiple therapies including antiviral, corticosteroids, and etoposide, the patient deteriorated and succumbed on day 10 of hospitalization. This case highlights the potential severity of influenza B and the need for early recognition to try and prevent complications such as ARDS and HLH.