{"title":"从显微镜下血尿到肾衰竭:IgA肾病的隐性进展。","authors":"Shriram Swaminathan, Bobby Chacko","doi":"10.31128/AJGP-01-25-7536","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis and a leading cause of chronic kidney disease globally. IgAN often presents with varied symptoms, and general practitioners (GPs) play a key role in its early detection and management.</p><p><strong>Objective: </strong>This review aims to provide GPs with an overview of IgAN, focusing on clinical presentations that warrant referral to nephrology and highlighting common pitfalls in primary care management with a case example.</p><p><strong>Discussion: </strong>Recognising high-risk features of IgAN through symptoms such as haematuria or proteinuria, addressing modifiable factors and understanding recent advances in management are vital for improving patient outcomes. New therapies targeting pathogenic pathways underscore the importance of collaborative care.</p>","PeriodicalId":54241,"journal":{"name":"Australian Journal of General Practice","volume":"54 10","pages":"711-715"},"PeriodicalIF":1.7000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"From microscopic haematuria to kidney failure: The hidden progression of IgA nephropathy.\",\"authors\":\"Shriram Swaminathan, Bobby Chacko\",\"doi\":\"10.31128/AJGP-01-25-7536\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis and a leading cause of chronic kidney disease globally. IgAN often presents with varied symptoms, and general practitioners (GPs) play a key role in its early detection and management.</p><p><strong>Objective: </strong>This review aims to provide GPs with an overview of IgAN, focusing on clinical presentations that warrant referral to nephrology and highlighting common pitfalls in primary care management with a case example.</p><p><strong>Discussion: </strong>Recognising high-risk features of IgAN through symptoms such as haematuria or proteinuria, addressing modifiable factors and understanding recent advances in management are vital for improving patient outcomes. New therapies targeting pathogenic pathways underscore the importance of collaborative care.</p>\",\"PeriodicalId\":54241,\"journal\":{\"name\":\"Australian Journal of General Practice\",\"volume\":\"54 10\",\"pages\":\"711-715\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Australian Journal of General Practice\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.31128/AJGP-01-25-7536\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Australian Journal of General Practice","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.31128/AJGP-01-25-7536","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
From microscopic haematuria to kidney failure: The hidden progression of IgA nephropathy.
Background: Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis and a leading cause of chronic kidney disease globally. IgAN often presents with varied symptoms, and general practitioners (GPs) play a key role in its early detection and management.
Objective: This review aims to provide GPs with an overview of IgAN, focusing on clinical presentations that warrant referral to nephrology and highlighting common pitfalls in primary care management with a case example.
Discussion: Recognising high-risk features of IgAN through symptoms such as haematuria or proteinuria, addressing modifiable factors and understanding recent advances in management are vital for improving patient outcomes. New therapies targeting pathogenic pathways underscore the importance of collaborative care.
期刊介绍:
The Australian Journal of General Practice (AJGP) aims to provide relevant, evidence-based, clearly articulated information to Australian general practitioners (GPs) to assist them in providing the highest quality patient care, applicable to the varied geographic and social contexts in which GPs work and to all GP roles as clinician, researcher, educator, practice team member and opinion leader. All articles are subject to peer review before they are accepted for publication.