热循环对纳米改性玻璃离子水泥的抗菌活性、接触角、表面粗糙度和显微硬度的影响:体外分析。

Q3 Dentistry
Shreejha Vasudevan, Jessy Paulraj, Subhabrata Maiti
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引用次数: 0

摘要

背景:纳米改性玻璃离子水门合剂在模拟口腔环境条件下的长期稳定性和性能需要进一步研究。目的:研究热循环对纳米改性玻璃离子水门铁的抗菌活性、接触角、表面粗糙度和显微硬度的影响。材料和方法:合成壳聚糖、钛、氧化锆和羟基磷灰石(Ch-Ti-Zr-HA)纳米颗粒,并通过一锅法组合成单一产品。随后将该产品掺入玻璃离聚体粉末中,制作浓度为3%、5%和10%的圆盘状改性GIC样品,分别命名为I组、II组和III组。第四组为对照,由常规玻璃离子水门合剂组成。进行表征。在热循环前后,对每组的抗菌活性和物理特性(如润湿性、表面粗糙度和显微硬度)进行评估。样品在55°C下进行热循环,停留时间为15秒,循环30,000次。所得资料采用非配对t检验进行统计学分析。结果:5% Ch-Ti-Zr-HA纳米改性GIC对变形链球菌(S. mutans)和乳酸菌的抗菌活性增强,在不影响材料硬度的情况下,具有更好的润湿性和最小的粗糙度(p < 0.05)。结论:Ch-Ti-Zr-HA纳米改性GIC具有较强的抗菌效果,增强了润湿性,降低了表面粗糙度,即使经过人工老化(热循环)也能提高显微硬度。这些发现表明,改善表面特性,可以最大限度地减少微生物粘附,并有助于持久的牙科修复材料。张建军,张建军,张建军,等。热循环对纳米改性玻璃离子水门柱表面粗糙度和显微硬度的影响。中华临床儿科杂志,2015;18(6):724-732。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Effects of Thermocycling on Antimicrobial Activity, Contact Angle, Surface Roughness, and Microhardness of Nanomodified Glass Ionomer Cement: An <i>In Vitro</i> Analysis.

Effects of Thermocycling on Antimicrobial Activity, Contact Angle, Surface Roughness, and Microhardness of Nanomodified Glass Ionomer Cement: An <i>In Vitro</i> Analysis.

Effects of Thermocycling on Antimicrobial Activity, Contact Angle, Surface Roughness, and Microhardness of Nanomodified Glass Ionomer Cement: An <i>In Vitro</i> Analysis.

Effects of Thermocycling on Antimicrobial Activity, Contact Angle, Surface Roughness, and Microhardness of Nanomodified Glass Ionomer Cement: An In Vitro Analysis.

Background: The long-term stability and performance of nanomodified glass ionomer cement under conditions mimicking the oral environment must be studied.

Aim: The aim of the study is to assess the effects of thermocycling on antimicrobial activity, contact angle, surface roughness, and microhardness of nanomodified glass ionomer cement.

Materials and methods: Chitosan, titanium, zirconia, and hydroxyapatite (Ch-Ti-Zr-HA) nanoparticles were synthesized and combined through a one-pot method to create a single product. This product was subsequently incorporated into glass ionomer powder, and disc-shaped modified GIC specimens were fabricated in concentrations of 3%, 5%, and 10%, designated as group I, group II, and group III, respectively. Group IV served as the control, consisting of conventional glass ionomer cement. Characterization was performed. Each group was evaluated for antimicrobial activity and physical characteristics such as wettability, surface roughness, and microhardness before and after thermocycling. The specimens were thermocycled at 55°C, with a dwell time of 15 seconds for 30,000 cycles. The obtained data were statistically analyzed using an unpaired t-test.

Results: Enhanced antimicrobial activity was observed in 5% Ch-Ti-Zr-HA nanomodified GIC against both Streptococcus mutans (S. mutans) and Lactobacillus, demonstrating improved performance with better wettability and least roughness without compromising material hardness (p < 0.05).

Conclusion: Ch-Ti-Zr-HA nanomodified GIC has strong antimicrobial efficacy, enhanced wettability, decreased surface roughness, and improved microhardness even after artificial aging (thermocycling). These findings indicate improved surface characteristics, which can minimize microbial adhesion and contribute to a durable dental restorative material.

How to cite this article: Vasudevan S, Paulraj J, Maiti S. Effects of Thermocycling on Antimicrobial Activity, Contact Angle, Surface Roughness, and Microhardness of Nanomodified Glass Ionomer Cement: An In Vitro Analysis. Int J Clin Pediatr Dent 2025;18(6):724-732.

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