{"title":"Schimke免疫-骨发育不良的牙面特征:从儿童期到青春期。","authors":"Alireza Sharifinejad, Fateme Parvizi, Maryam Enteghad, Yasamin Ghahramani","doi":"10.1002/ccr3.70921","DOIUrl":null,"url":null,"abstract":"<p>Schimke immune-osseous dysplasia (SIOD) is a sporadic multi-system disorder mainly characterized by spondyloepiphyseal dysplasia, immune insufficiency, and renal failure. Little evidence is available regarding the dentofacial features of SIOD. This study presents the clinical course of a 16-year-old girl suffering from SIOD, focusing on her oral anomalies from her mixed to permanent dentition. After kidney transplantation and immune therapy, the patient discussed herein is supposed to live longer than a majority of the Schimke population. These findings might play a role in the earlier diagnosis of the syndrome and can better emphasize oral care throughout their lives. This is the first study that thoroughly discusses the dental anomalies of an SIOD patient from her mixed to permanent dentition.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 10","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12485268/pdf/","citationCount":"0","resultStr":"{\"title\":\"Dentofacial Features in Schimke Immuno-Osseous Dysplasia: From Childhood to Adolescence\",\"authors\":\"Alireza Sharifinejad, Fateme Parvizi, Maryam Enteghad, Yasamin Ghahramani\",\"doi\":\"10.1002/ccr3.70921\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Schimke immune-osseous dysplasia (SIOD) is a sporadic multi-system disorder mainly characterized by spondyloepiphyseal dysplasia, immune insufficiency, and renal failure. Little evidence is available regarding the dentofacial features of SIOD. This study presents the clinical course of a 16-year-old girl suffering from SIOD, focusing on her oral anomalies from her mixed to permanent dentition. After kidney transplantation and immune therapy, the patient discussed herein is supposed to live longer than a majority of the Schimke population. These findings might play a role in the earlier diagnosis of the syndrome and can better emphasize oral care throughout their lives. This is the first study that thoroughly discusses the dental anomalies of an SIOD patient from her mixed to permanent dentition.</p>\",\"PeriodicalId\":10327,\"journal\":{\"name\":\"Clinical Case Reports\",\"volume\":\"13 10\",\"pages\":\"\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12485268/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.70921\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.70921","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Dentofacial Features in Schimke Immuno-Osseous Dysplasia: From Childhood to Adolescence
Schimke immune-osseous dysplasia (SIOD) is a sporadic multi-system disorder mainly characterized by spondyloepiphyseal dysplasia, immune insufficiency, and renal failure. Little evidence is available regarding the dentofacial features of SIOD. This study presents the clinical course of a 16-year-old girl suffering from SIOD, focusing on her oral anomalies from her mixed to permanent dentition. After kidney transplantation and immune therapy, the patient discussed herein is supposed to live longer than a majority of the Schimke population. These findings might play a role in the earlier diagnosis of the syndrome and can better emphasize oral care throughout their lives. This is the first study that thoroughly discusses the dental anomalies of an SIOD patient from her mixed to permanent dentition.
期刊介绍:
Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).